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<channel>
	<title>MDCalc &#187; Hematology/Oncology</title>
	<atom:link href="http://www.mdcalc.com/cat/specialties/hematologyoncology/feed" rel="self" type="application/rss+xml" />
	<link>http://www.mdcalc.com</link>
	<description>click, diagnose, treat.</description>
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			<item>
		<title>Glasgow-Blatchford Bleeding Score (GBS)</title>
		<link>http://www.mdcalc.com/glasgow-blatchford-bleeding-score-gbs</link>
		<comments>http://www.mdcalc.com/glasgow-blatchford-bleeding-score-gbs#comments</comments>
		<pubDate>Thu, 08 Oct 2009 03:34:18 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Critical Care]]></category>
		<category><![CDATA[Gastroenterology]]></category>
		<category><![CDATA[Gastrointestinal]]></category>
		<category><![CDATA[Hematology]]></category>
		<category><![CDATA[Hematology/Oncology]]></category>
		<category><![CDATA[Hepatology]]></category>
		<category><![CDATA[Score]]></category>

		<guid isPermaLink="false">http://www.mdcalc.com/?p=518</guid>
		<description><![CDATA[

Is patient female?  Yes

Hemoglobin g/dL

BUN mg/dL

Initial Systolic Blood Pressure mm Hg

Heart Rate &#8805; 100  Yes
Does the patient have melena?  Yes
Did the patient have syncope?  Yes
Does the patient have hepatic disease?  Yes
Does the patient have heart failure?  Yes


Score points
 



Glasgow-Blatchford Score


Blood Urea



≥6·5 &#60;8·0
2


≥8·0 &#60;10·0
3


≥10·0 &#60;25·0

4


≥25
6


Hemoglobin (g/L) for men


≥12.0 &#60;13.0

1


≥10.0 &#60;12.0
3


&#60;10.0
6



Hemoglobin [...]]]></description>
			<content:encoded><![CDATA[<form action="get" name="theform">
<table cellpadding="0" cellspacing="0" border="0">
<tr class="req"><td>Is patient female? </td><td><input name="female" onclick="GlasgowBlatchford();" type="checkbox"> Yes</td></tr>

<tr class="req"><td>Hemoglobin</td><td><input type="text" name="hgb" onBlur="GlasgowBlatchford();" size="5"> <label id="label1">g/dL</label></td></tr>

<tr class="req"><td>BUN</td><td><input type="text" name="bun" onBlur="GlasgowBlatchford();" size="5"> <span id="label2">mg/dL</span></td></tr>

<tr class="req"><td>Initial Systolic Blood Pressure</td><td><input type="text" name="sbp" onBlur="GlasgowBlatchford();" size="5"> mm Hg</td></tr>

<tr class="req"><td>Heart Rate &ge; 100 </td><td><input name="hr" onclick="GlasgowBlatchford();" type="checkbox"> Yes</td></tr>
<tr class="req"><td>Does the patient have melena? </td><td><input name="melena" onclick="GlasgowBlatchford();" type="checkbox"> Yes</td></tr>
<tr class="req"><td>Did the patient have syncope? </td><td><input name="syncope" onclick="GlasgowBlatchford();" type="checkbox"> Yes</td></tr>
<tr class="req"><td>Does the patient have hepatic disease? </td><td><input name="hepatic" onclick="GlasgowBlatchford();" type="checkbox"> Yes</td></tr>
<tr class="req"><td>Does the patient have heart failure? </td><td><input name="chf" onclick="GlasgowBlatchford();" type="checkbox"> Yes</td></tr>


<tr class="answer"><td>Score</td><td><input name="result" onfocus="this.blur()" value="Click!"  readonly="readonly" type="text" /> points</td></tr>
<tr class="answer"><td colspan="2"><div id="resultmsg"> </div></td></tr>
</table></form>

<div id="formula">
<p>Glasgow-Blatchford Score
<table class="data">
<tr>
<th colspan="2">Blood Urea</th>
</tr>
<tr>

<td>≥6·5 &lt;8·0</td>
<td>2</td>
</tr>
<tr>
<td>≥8·0 &lt;10·0</td>
<td>3</td>
</tr>
<tr>
<td>≥10·0 &lt;25·0</td>

<td>4</td>
</tr>
<tr>
<td>≥25</td>
<td>6</td>
</tr>
<tr>
<th colspan="2">Hemoglobin (g/L) for men</th>
</tr>
<tr>
<td>≥12.0 &lt;13.0</td>

<td>1</td>
</tr>
<tr>
<td>≥10.0 &lt;12.0</td>
<td>3</td>
</tr>
<tr>
<td>&lt;10.0</td>
<td>6</td>
</tr>
<tr>

<th colspan="2">Hemoglobin (g/L) for women</th>
</tr>
<tr>
<td>≥10.0 &lt;12.0</td>
<td>1</td>
</tr>
<tr>
<td>&lt;10.0</td>
<td>6</td>
</tr>
<tr>

<th colspan="2">Systolic blood pressure (mm Hg)</th>
</tr>
<tr>
<td>100–109</td>
<td>1</td>
</tr>
<tr>
<td>90–99</td>
<td>2</td>
</tr>
<tr>
<td>&lt;90</td>

<td>3</td>
</tr>
<tr>
<td>Pulse ≥100 (per min)</td>
<td>1</td>
</tr>
<tr>
<td>Presentation with melaena</td>
<td>1</td>

</tr>
<tr>
<td>Presentation with syncope</td>
<td>2</td>
</tr>
<tr>
<td>Hepatic disease</td>
<td>2</td>
</tr>
<tr>
<td>Cardiac failure</td>
<td>2</td>

</tr>



</table></p>
</div>

<div id="usage">
<p>Low risk = Score of 0. Any score higher than 0 is "high risk" for needing a medical intervention of transfusion, endoscopy, or surgery.</p>
</div>

<div id="source">
<p><a href="http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2800%2902816-6/fulltext">A risk score to predict need for treatment for uppergastrointestinal haemorrhage. Lancet 2000.</a></p>
<p><a href="http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2800%2902816-6/abstract">A risk score to predict need for treatment for uppergastrointestinal haemorrhage. The Lancet, 2000.</a></p>
<p><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?itool=abstractplus&#038;db=pubmed&#038;cmd=Retrieve&#038;dopt=abstractplus&#038;list_uids=17870480">A risk score to predict need for treatment for uppergastrointestinal haemorrhage.  Am J Emerg Med. 2007.</a></p>
<p><a href="http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2808%2961769-9/abstract#">Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation. The Lancet, 2009.</a></p>
<p><a href="http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2808%2961769-9/abstract#">Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation. The Lancet, 2009.</a></p>
</div> ]]></content:encoded>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Well&#8217;s Criteria for DVT</title>
		<link>http://www.mdcalc.com/wells-criteria-for-dvt</link>
		<comments>http://www.mdcalc.com/wells-criteria-for-dvt#comments</comments>
		<pubDate>Sat, 28 Feb 2009 14:44:33 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Cardiac]]></category>
		<category><![CDATA[Cardiology]]></category>
		<category><![CDATA[Hematology]]></category>
		<category><![CDATA[Hematology/Oncology]]></category>
		<category><![CDATA[Score]]></category>

		<guid isPermaLink="false">http://www.mdcalc.com/mdcalc/wordpress/?p=362</guid>
		<description><![CDATA[


Active cancer? Yes +1
Bedridden recently >3 days or major surgery within four weeks? Yes +1
Calf swelling >3cm compared to the other leg? Yes +1
Collateral (nonvaricose) superficial veins present? Yes +1
Entire leg swollen? Yes +1
Localized tenderness along the deep venous system? Yes +1
Pitting edema, greater in the symptomatic leg? Yes +1
Paralysis, paresis, or recent plaster immobilization [...]]]></description>
			<content:encoded><![CDATA[<form action="get" name="theform">
<table cellpadding="0" cellspacing="0" border="0">

<tr><td>Active cancer?</td><td><input type="checkbox" name="cancer" onClick="WellsDVT();" > Yes <small>+1</small></td></tr>
<tr><td>Bedridden recently >3 days or major surgery within four weeks?</td><td><input type="checkbox" name="bed" onClick="WellsDVT();"> Yes <small>+1</small></td></tr>
<tr><td>Calf swelling >3cm compared to the other leg?</td><td><input type="checkbox" name="calf" onClick="WellsDVT();" > Yes <small>+1</small></td></tr>
<tr><td>Collateral (nonvaricose) superficial veins present?</td><td><input type="checkbox" name="collateral" onClick="WellsDVT();" > Yes <small>+1</small></td></tr>
<tr><td>Entire leg swollen?</td><td><input type="checkbox" name="entireleg" onClick="WellsDVT();"> Yes <small>+1</small></td></tr>
<tr><td>Localized tenderness along the deep venous system?</td><td><input type="checkbox" name="local" onClick="WellsDVT();"> Yes <small>+1</small></td></tr>
<tr><td>Pitting edema, greater in the symptomatic leg?</td><td><input type="checkbox" name="edema" onClick="WellsDVT();"> Yes <small>+1</small></td></tr>
<tr><td>Paralysis, paresis, or recent plaster immobilization of the lower extremity</td><td><input type="checkbox" name="paralysis" onClick="WellsDVT();"> Yes <small>+1</small></td></tr>
<tr><td>Alternative diagnosis to DVT as likely or more likely?</td><td><input type="checkbox" name="alt" onClick="WellsDVT();"> Yes <small>-2</small></td></tr>


<tr class="answer"><td>Score </td><td><input name="result" onfocus="this.blur()" value="Click!"  readonly="readonly" type="text" />  Points</td></tr>
<tr class="msg"><td colspan="2"><div id="resultmsg"> </div></td></tr></table></form>

<div id="source">
<ul>
<li><a href="http://www.ncbi.nlm.nih.gov/pubmed/16403932">Does this patient have deep vein thrombosis? Wells PS, Owen C, Doucette S, Fergusson D, Tran H. JAMA. 2006 Jan 11;295(2):199-207. Review.</a></li>
<li><a href="http://www.ncbi.nlm.nih.gov/pubmed/17060659">Diagnosis and treatment of deep-vein thrombosis. Scarvelis D, Wells PS. CMAJ. 2006 Oct 24;175(9):1087-92. Review. Erratum in: CMAJ. 2007 Nov 20;177(11):1392.</a></li>
<li><a href="http://www.ncbi.nlm.nih.gov/pubmed/14507948">Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis. Wells PS, Anderson DR, Rodger M, Forgie M, Kearon C, Dreyer J, Kovacs G, Mitchell M, Lewandowski B, Kovacs MJ. N Engl J Med. 2003 Sep 25;349(13):1227-35.</a></li>
</ul>
 </div>]]></content:encoded>
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		</item>
		<item>
		<title>Well&#8217;s Criteria for Pulmonary Embolism / PE</title>
		<link>http://www.mdcalc.com/wells-criteria-for-pulmonary-embolism-pe</link>
		<comments>http://www.mdcalc.com/wells-criteria-for-pulmonary-embolism-pe#comments</comments>
		<pubDate>Fri, 02 Jan 2009 04:35:11 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Cardiac]]></category>
		<category><![CDATA[Cardiology]]></category>
		<category><![CDATA[Critical Care]]></category>
		<category><![CDATA[Hematology]]></category>
		<category><![CDATA[Hematology/Oncology]]></category>
		<category><![CDATA[Pulmonology]]></category>
		<category><![CDATA[Respiratory]]></category>
		<category><![CDATA[Score]]></category>

		<guid isPermaLink="false">http://localhost:8888/mdcalc/wordpress/?p=115</guid>
		<description><![CDATA[


Clinical Signs and Symptoms of DVT? Yes +3
PE Is #1 Diagnosis, or Equally Likely Yes +3
Heart Rate > 100? Yes +1.5
Immobilization at least 3 days, or Surgery in the Previous 4 weeks Yes +1.5

Previous, objectively diagnosed PE or DVT? Yes +1.5


Hemoptysis? Yes +1
Malignancy w/ Treatment within 6 mo, or palliative? Yes +1


Score    [...]]]></description>
			<content:encoded><![CDATA[<form action="get" name="theform">
<table cellpadding="0" cellspacing="0" border="0">

<tr class="req"><td>Clinical Signs and Symptoms of DVT?</td><td><input type="checkbox" name="dvt" onClick="Wells();" > Yes <small>+3</small></td></tr>
<tr class="req"><td>PE Is #1 Diagnosis, or Equally Likely</td><td><input type="checkbox" name="pe" onClick="Wells();" > Yes <small>+3</small></td></tr>
<tr class="req"><td>Heart Rate > 100?</td><td><input type="checkbox" name="hr" onClick="Wells();" > Yes <small>+1.5</small></td></tr>
<tr class="req"><td>Immobilization at least 3 days, or Surgery in the Previous 4 weeks</td><td><input type="checkbox" name="immob" onClick="Wells();"> Yes <small>+1.5</small></td></tr>

<tr class="req"><td>Previous, objectively diagnosed PE or DVT?</td><td><input type="checkbox" name="prevpe" onClick="Wells();"> Yes <small>+1.5</small></td></tr>


<tr class="req"><td>Hemoptysis?</td><td><input type="checkbox" name="hemop" onClick="Wells();"> Yes <small>+1</small></td></tr>
<tr class="req"><td>Malignancy w/ Treatment within 6 mo, or palliative?</td><td><input type="checkbox" name="ca" onClick="Wells();"> Yes <small>+1</small></td></tr>


<tr class="answer"><td>Score </td><td><input name="result" onfocus="this.blur()" value="Click!"  readonly="readonly" type="text" />   </td></tr>
<tr class="msg"><td colspan="2"><div id="resultmsg"> </div></td></tr></table></form>

<div id="source"><p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&#038;db=pubmed&#038;dopt=Abstract&#038;list_uids=10744147&#038;query_hl=2&#038;itool=pubmed_docsum">Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer.</a> Thromb Haemost. 2000 Mar;83(3):416-20.</p> </div>]]></content:encoded>
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		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Absolute Reticulocyte Count (Reticulocyte Index)</title>
		<link>http://www.mdcalc.com/absolute-reticulocyte-count-index</link>
		<comments>http://www.mdcalc.com/absolute-reticulocyte-count-index#comments</comments>
		<pubDate>Fri, 02 Jan 2009 03:28:56 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Equation]]></category>
		<category><![CDATA[Hematology]]></category>
		<category><![CDATA[Hematology/Oncology]]></category>

		<guid isPermaLink="false">http://localhost:8888/mdcalc/wordpress/?p=12</guid>
		<description><![CDATA[



 Percentage or # Retics  % 

Pt's Hct  

Normal Hct (depends on sex and lab norm)   



Absolute Reticulocyte Count      



Reticulocyte Index





Absolute Reticulocyte Count = # or % retics * (Pt's Hct / Normal Hct) 
Reticulocyte Index = Absolute Retic Ct / Maturation Factor 
Maturation Factors:

Hct &#8805; [...]]]></description>
			<content:encoded><![CDATA[<form action="get" name="theform">
<table cellpadding="0" cellspacing="0" border="0">

<tr class="req">
<td> Percentage or # Retics </td><td><input type="text" name="v1" onBlur="AbsRetic();" size="5"> % </td></tr>

<tr class="req"><td>Pt's Hct </td><td><input type="text" name="v2" onBlur="AbsRetic();" size="5"> </td></tr>

<tr class="req"><td>Normal Hct (depends on sex and lab norm) </td><td><input type="text" name="v3" onBlur="AbsRetic();" size="5">  </td></tr>



<tr class="answer"><td>Absolute Reticulocyte Count </td><td><input name="result" onfocus="this.blur()" value="Click!"  readonly="readonly" type="text" />     </td></tr>



<tr class="answer"><td>Reticulocyte Index</td><td><input name="result2" readonly="readonly" type="text" size="5"></td></tr>

</table></form>


<div id="formula">
<p>Absolute Reticulocyte Count = # or % retics * (Pt's Hct / Normal Hct) <br/>
Reticulocyte Index = Absolute Retic Ct / Maturation Factor <br/>
<p>Maturation Factors:</p>
<ul>
<li>Hct &ge; 35%: 1.0</li>
<li>35% &gt; Hct &ge; 25%: 1.5</li>
<li>25% &gt; Hct &ge; 20%: 2.0</li>
<li>20% &gt; Hct: 2.5</li>
</div>

<div id="usage">

<p>Retic Index > 2% = adequate response; < 2% = hypoproliferation</p>

</div>]]></content:encoded>
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		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Absolute Neutrophil Count (ANC)</title>
		<link>http://www.mdcalc.com/absolute-neutrophil-count-anc</link>
		<comments>http://www.mdcalc.com/absolute-neutrophil-count-anc#comments</comments>
		<pubDate>Fri, 02 Jan 2009 03:26:08 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Critical Care]]></category>
		<category><![CDATA[Equation]]></category>
		<category><![CDATA[Hematology]]></category>
		<category><![CDATA[Hematology/Oncology]]></category>
		<category><![CDATA[Immunology]]></category>

		<guid isPermaLink="false">http://localhost:8888/mdcalc/wordpress/?p=9</guid>
		<description><![CDATA[



 Percentage Neutrophils  % 

Percentage Bands % 

WBC (per 1000. Usually reported as "8.4"; do not enter 8400.)   cells/ml 



Absolute Neutrophil Count  cells/ml     






Absolute Neutrophil Count = 10 * WBC count in 1000s  * (% PMNs + % Bands)






Neutropenia: ANC < 1500 cells / mm3

Mild Neutropenia: [...]]]></description>
			<content:encoded><![CDATA[<form action="get" name="theform">
<table cellpadding="0" cellspacing="0" border="0">

<tr class="req">
<td> Percentage Neutrophils </td><td><input type="text" name="v1" onBlur="AbsNeutrophil();" size="5"> % </td></tr>

<tr class="req"><td>Percentage Bands</td><td><input type="text" name="v2" onBlur="AbsNeutrophil();" size="5"> % </td></tr>

<tr class="req"><td>WBC (per 1000. Usually reported as "8.4"; do not enter 8400.) </td><td><input type="text" name="v3" onBlur="AbsNeutrophil();" size="5">  cells/ml </td></tr>



<tr class="answer"><td>Absolute Neutrophil Count </td><td><input name="result" onfocus="this.blur()" value="Click!"  readonly="readonly" type="text" /> cells/ml     </td></tr>

</table></form>


<div id="formula">

<p>Absolute Neutrophil Count = 10 * WBC count in 1000s  * (% PMNs + % Bands)</p>

</div>


<div id="usage">

<p>Neutropenia: ANC < 1500 cells / mm<sup>3</sup></p>
<ul>
<li>Mild Neutropenia: 1000-1500 cells / mm<sup>3</sup></li>
<li>Moderate Neutropenia: 500-999 cells / mm<sup>3</sup></li>
<li>Severe Neutropenia: < 500 cells / mm<sup>3</sup></li>
</ul>

<p>Filgrastim (Neupogen), aka G-CSF, can stimulate production of neutrophils. </p>

</div>]]></content:encoded>
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