Transtubular Potassium Gradient (TTKG)

Determines if potassium derangements are due to renal or extra-renal cause.

Transtubular Potassium Gradient (TTKG) = (P_Osm * U_Potassium ) / (P_Potassium x U_Osm)

Note that this formula is valid only when Uosm >300 and UNa >25. This test can help determine the source of potassium imbalance.

Posted in: Endocrine/Metabolic • Endocrinology • Nephrology • Renal