PO

Loading dose is 140mg/kg PO, then 17 more doses every 4 hours of 70mg/kg PO. If patient vomits within 1 hour of dose, it must be repeated.  

IV

Patients >40 kg:

• Loading Dose: 150 mg/kg in 200 mL of diluent administered over 60 min
• Dose 2: 50 mg/kg in 500 mL of diluent administered over 4 hr
• Dose 3: 100 mg/kg in 1000 mL of diluent administered over 16 hr

Patients >20 - <40kg

• Loading Dose: 150 mg/kg in 100 mL of diluent administered over 60 min
• Dose 2: 50 mg/kg in 250 mL of diluent administered over 4 hr
• Dose 3: 100 mg/kg in 500 mL of diluent administered over 16 hr

Patients <20kg

• Loading Dose: 150 mg/kg in 3 mL/kg of body weight of diluent administered over 60 min
• Dose 2: 50 mg/kg in 7 mL/kg of body weight of diluent administered over 4 hr
• Dose 3: 100 mg/kg in 14 mL/kg of body weight of diluent administered over 16 hr

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