Calculations must be re-checked, shouldn't be used alone for patient care, and don't substitute for professional judgment. See our full disclaimer.
Calculates PO/IV NAC dosing for acetaminophen overdose (and nomogram to determine toxic 4 hour level).
Loading dose is 140mg/kg PO, then 17 more doses every 4 hours of 70mg/kg PO. If patient vomits within 1 hour of dose, it must be repeated.
Patients >40 kg:
Patients >20 - 40kg
Patients <20 kg
Acetadote Dosing Website and Dosing Insert PDF
Calculations must be re-checked and should not be used alone to guide patient care nor should they substitute for clinical judgement. disclaimer