Fractional Excretion of Sodium (FENa)

Determines if renal failure is due to pre-renal, post-renal, or intrinsic renal pathology.

Serum Na
Urine Na
Serum Cr
Urine Cr
FENa %
Prerenal Intrinsic Renal Postrenal
UNa (mmol/L) <20 >40 >40
FENa <1% >1% >4%

Prerenal: Anything that causes decreased effective renal perfusion: Hypovolemia, CHF, Renal Artery Stenosis, Sepsis, etc. Remember, contrast-induced nephropathy will often look pre-renal.

Intrinsic Renal: ATN, AIN, Glomerulonephritides, etc

Postrenal: Obstruction (BPH, bladder stone, bilateral ureter obstruction)

Fractional Excretion of Sodium (FENa) = (PCr * UNa ) / (PNa x UCr) %

Posted in: Critical CareNephrologyRenal









The NNT : Quick Summaries of Evidence-Based Medicine