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Calculations must be re-checked, shouldn't be used alone for patient care, and don't substitute for professional judgment. See our full disclaimer.
Corrects a phenytoin serum level for renal failure and/or hypoalbuminemia.
Corrected Phenytoin = Measured Phenytoin Level / ( (adjustment x albumin) + 0.1)
Adjustment = 0.2; In patients with Creatinine Clearance < 20, adjustment = 0.1.
The “Sheiner-Tozer Equation” is the official name of this correction.
Calculations must be re-checked and should not be used alone to guide patient care nor should they substitute for clinical judgement. disclaimer