Phenytoin/Dilantin Correction for Albumin or Renal Failure

Corrects a phenytoin serum level for renal failure and/or hypoalbuminemia.

Patient's calculated Creatinine Clearance < 20?
Phenytoin Level
Serum Albumin
Corrected Phenytoin
The Sheiner-Tozer Equation is Used for an Accurate Estimate:
Corrected Phenytoin = Measured Phenytoin Level / ( (adjustment x albumin) + 0.1)

Adjustment = 0.2; In patients with Creatinine Clearance < 20, adjustment = 0.1.

Posted in: Critical CareNeurologicNeurology









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