Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm

    Disease

    Select...

    Specialty

    Select...

    Chief Complaint

    Select...

    Organ System

    Select...

    Patent Pending

    Absolute Reticulocyte Count & Reticulocyte Index

    Assesses appropriate response to anemia, frequently in sickle cell patients.
    Favorite
    When to Use
    Why Use

    Determining if an anemic patient is mounting an appropriate response to their anemia, or if they have an inadequate marrow response (either from the marrow itself or a nutrient deficiency, or the blood loss was too rapid for reticulocyte response).

    The laboratory “reticulocyte count” is actually a percentage. The absolute count corrects for the level of anemia, and the reticulocyte index determines if the reticulocyte count is appropriate for the level of anemia.

    %
    %
    %

    Result:

    Please fill out required fields.

    Next Steps
    Evidence
    Creator Insights

    Advice

    • Patients with an appropriate marrow response (high reticulocyte index) typically are not evaluated further.
    • Patients with an inappropriate marrow response (low reticulocyte index) may be further evaluated for nutritional deficiencies or marrow abnormalities.
    • Always consider transfusion and/or iron supplementation in anemic patients.

    Formula

    Absolute Reticulocyte Count = # or % retics * (Pt's Hct / Normal Hct)

    Reticulocyte Index = Absolute Retic Ct / Maturation Factor

    Maturation Factors:

    • Hct ≥ 35%: 1.0
    • 35% > Hct ≥ 25%: 1.5
    • 25% > Hct ≥ 20%: 2.0
    • 20% > Hct: 2.5

    Facts & Figures

    Retic Index > 2% = adequate response; < 2% = hypoproliferation

    Poorana Priya

    About the Creator

    Poorana Priya is a postgraduate pathologist practicing in India at Sree Balaji Medical College & Hospital.