Lee DW, Gardner R, Porter DL, et al. Current concepts in the diagnosis and management of cytokine release syndrome. Blood. 2014;124(2):188-95. 

Park JH, Romero FA, Taur Y, et al. Cytokine Release Syndrome Grade is a Predictive Marker for Infections in Relapsed or Refractory B-cell All Patients Treated with CAR T Cells. Clin Infect Dis. 2018.

Porter D, Frey N, Wood PA, Weng Y, Grupp SA. Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel. J Hematol Oncol. 2018;11(1):35.

OTHER

Cytokine Release Syndrome (CRS) Grading

toxicity

comorbidities

<p>Assesses severity of CRS in patients on immunotherapy.</p>

The Cytokine Release Syndrome Grading scales the degrees of severity of CRS. 

Fong Score

CRASH

Duval/CIBMTR Score

EB Medicine is the premier provider of evidence-based clinical content and CME resources for emergency medicine practitioners.

Listen to the VACO co-creators break down how to use VACO\, what it does\, and what it doesn’t.

Calc Function