Jalan R, Saliba F, Pavesi M, et al. Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure. J Hepatol. 2014;61(5):1038-47.

Moreau R, Jalan R, Gines P, et al. Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. Gastroenterology. 2013;144(7):1426-37, 1437.e1-9.

Lee M, Lee JH, Oh S, et al. CLIF-SOFA scoring system accurately predicts short-term mortality in acutely decompensated patients with alcoholic cirrhosis: a retrospective analysis. Liver Int. 2015;35(1):46-57.

Engelmann C, Thomsen KL, Zakeri N, et al. Validation of CLIF-C ACLF score to define a threshold for futility of intensive care support for patients with acute-on-chronic liver failure. Crit Care. 2018;22(1):254.

Dr. Rajiv Jalan

CLIF-C ACLF (Acute-on-Chronic Liver Failure)

bili

grade

resp

resp1

resp2

Predicts mortality in acute-on-chronic liver failure.

CLIF-C ACLF

Callum Wood, MB, BChir, MRCP (UK)

The CLIF-C ACLF (Acute-on-Chronic Liver Failure) predicts mortality in acute-on-chronic liver failure.

White Blood Cell Count

MELD Na (UNOS/OPTN)

Child-Pugh Score

UKELD Score

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Listen to the VACO co-creators break down how to use VACO\, what it does\, and what it doesn’t.

Calc Function