Rome IV Diagnostic Criteria for Opioid-Induced Constipation
Use in patients with symptoms suggestive of constipation in the setting of opioid use.
Patients with any of the following features must be evaluated clinically for other diagnoses even though opioid induced constipation may be present:
Signs or symptoms of gastrointestinal bleeding.
Unexplained iron deficiency anemia.
Unintentional weight loss.
Palpable abdominal mass or lymphadenopathy on exam.
Family history of colon cancer and have not had age-appropriate colon cancer screening.
Onset of symptoms age ≥50 years and have not had age-appropriate colon cancer screening.
Sudden or acute onset of new change in bowel habit that occurred prior to initiation or dose change of an opioid.
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