Rome IV Diagnostic Criteria for Infant Regurgitation
INSTRUCTIONS
Use in infants 3 weeks to 12 months with regurgitation for at least 3 weeks.
Patients with any of the following alarm features should be evaluated clinically for other diagnoses:
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Excessive irritability.
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Onset <3 weeks, > 6 months or persistence >12 months of age.
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Retching and/or persistent forceful vomiting.
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Bilious or nocturnal vomiting.
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Hematemesis.
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Aspiration.
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Respiratory symptoms (wheezing, stridor, cough, hoarseness).
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Apnea.
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BRUE (Brief Resolved Unexplained Event).
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Weight loss or failure to thrive.
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Feeding or swallowing difficulties including food refusal.
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Abnormal neurologic exam, posturin or seizures
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Dystonic neck posturing (Sandifer syndrome).
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Chronic diarrhea or constipation.
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Rectal bleeding.
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Macro or Microcephaly.
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Bulging fontanelle.
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Hepatosplenomegaly.
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Abdominal tenderness or distension.
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Documented or suspected genetic/metabolic syndrome.
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Fever.
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Lethargy.
Diagnostic Result:
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- Beate Beinvogl, MD, MPH
- Samuel Nurko, MD, MPH