Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm





    Chief Complaint


    Organ System


    Patent Pending

    Winters' Formula for Metabolic Acidosis Compensation

    Calculates the expected pCO₂ compensation in a purely metabolic acidosis.
    When to Use
    Why Use
    • A patient with a suspect pure metabolic acidosis.
    • A patient with a mixed acidosis to determine level of compensation.

    In a compensated state, a patient with a metabolic acidosis should be able to compensate by developing a respiratory alkalosis. Winters' Formula predicts this level of “appropriate” compensation.



    Please fill out required fields.

    Next Steps
    Creator Insights
    Dr. August Supervia

    About the Creator

    August Supervia, MD, is a practicing physician in the emergency department at Hospital Universitari del Mar in Barcelona, Spain. He is an active researcher and a member of the European Respiratory Society.

    To view Dr. August Supervia's publications, visit PubMed

    Are you Dr. August Supervia? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    About the Creator
    Dr. August Supervia
    Are you Dr. August Supervia?