Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med. 1987 Dec 24;317(26):1625-9. PMID: 3317057.

Lewis JD, et. al. Use of the Non-invasive Components of the Mayo Score to Assess Clinical Response in Ulcerative Colitis. Inflamm Bowel Dis. Dec 2008; 14(12): 1660–1666. doi: 10.1002/ibd.20520.

Sutherland LR, et al. 5-Aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctitis. Gastroenterology 92.6; 1987: 1894-1898.

Paine ER. Colonoscopic evaluation in ulcerative colitis. Gastroenterology report 2.3; 2014: 161-168.

D’Haens G, et al. A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis. Gastroenterology 132.2; 2007: 763-786.

Manginot C et al. An endoscopic Mayo score of 0 is associated with a lower risk of colectomy than a score of 1 in ulcerative colitis. Gut 64.7; 2015: 1181.

Irvine EJ, et al. Quality of life: a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Canadian Crohn's Relapse Prevention Trial Study Group. Gastroenterology 106.2; 1994: 287-296.

Sandborn WJ, et al. Ozanimod Induction and Maintenance Treatment for Ulcerative Colitis. New England Journal of Medicine 374.18; 2016: 1754-1762.

Travis SPL, et. al. Reliability and Initial Validation of the Ulcerative Colitis Endoscopic Index of Severity. Gastroenterology. 2013;145:987–995.

Dr. Kenneth W. Schroeder

var calc_output = [];

var u = parseFloat(stool)+parseFloat(rectal)+parseFloat(mucos)+parseFloat(rating);
var msg = 'Scores should be compared to previous scores taken for a patient. The higher the score (maximum 12 points), the more severe the ulcerative colitis.';
var mini_msg = 'Higher scores (maximum 12 points) indicate more severe ulcerative colitis.';

calc_output.push({ name: 'mini', value: u, value_text: 'points', message: mini_msg });
calc_output.push({ name: 'Mayo DAI', value: u, value_text: 'points', message: msg });

Mayo Score / Disease Activity Index (DAI) for Ulcerative Colitis

stool

rectal

mucos

rating

Assesses severity of ulcerative colitis.

Mayo DAI for Ulcerative Colitis

John Vizuete, MD, MPH, is currently a senior gastroenterology fellow at the University of Texas Health Science Center at San Antonio. A native Texan, Dr. Vizuete obtained his BA at the University of Texas at Austin, followed by medical school and internal medicine residency training at UTHSCSA. He also holds a master’s degree in public health. Dr. Vizuete is interested in clinical outcomes in gastrointestinal bleeding, luminal endoscopy, and inflammatory bowel disease and is actively involved in medical education.

John Vizuete, MD, MPH

Mayo Score / Disease Activity Index (DAI) for Ulcerative Colitis assesses severity of current ulcerative colitis.

Montreal Classification for IBD

Truelove/Witts Severity Index for UC

UCEIS

EB Medicine is the premier provider of evidence-based clinical content and CME resources for emergency medicine practitioners.

Listen to the VACO co-creators break down how to use VACO\, what it does\, and what it doesn’t.

Calc Function