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    Patent Pending

    Estimated Ethanol (and Toxic Alcohol) Serum Concentration Based on Ingestion

    Predicts ethanol concentration based on ingestion of alcohol.


    Allows estimation of maximal predicted serum concentration of alcohol based on volume and concentration ingested. Assumes 0.6 L/kg volume of distribution.

    When to Use
    Why Use

    Predicting serum concentration of toxic alcohols.

    • The formula makes several assumptions to approximate maximal predicted serum concentration:
      • Complete alcohol absorption.
      • Absence of alcohol metabolism or elimination.
      • Absence of volume contraction effects.
      • Alcohol specific gravity disregarded.
      • Gender and age differences in pharmacokinetics discounted.
    • The estimated serum concentration from ingestion of a given volume of alcohol will differ depending on which alcohol is ingested.

    Estimates maximal predicted serum concentration of alcohol based on volume and concentration ingested.

    Ethylene glycol
    Diethylene glycol


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    Creator Insights
    Dr. Mary Ann Howland

    About the Creator

    Mary Ann Howland, PharmD, is an adjunct professor at the Ronald O. Perelman Department of Emergency Medicine at NYU Langone Health and a clinical professor at the College of Pharmacy and Health Sciences at St. John's University. She specializes in clinical toxicology, poison control, and clinical toxicological management. Dr. Howland's work has been published in many books and journals, including Goldfrank's Toxicologic Emergencies.

    To view Dr. Mary Ann Howland's publications, visit PubMed

    Are you Dr. Mary Ann Howland? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
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