Revised Multiple Myeloma International Staging System (R-ISS)
Prognostication tool for myeloma patients based on the genetics and other routinely used lab values in conjunction with the original ISS Staging System.
INSTRUCTIONS
Use only in patients recently diagnosed with multiple myeloma. Do not use in patients with relapsed myeloma, smoldering myeloma or MGUS.
When to Use
Pearls/Pitfalls
Why Use
<3.5 mg/L
3.5-5.4 mg/L
>5.4 mg/L
<3.5 g/dL
≥3.5 g/dL
Standard risk
High risk
Normal (< upper limit of normal)
High (> upper limit of normal)
Result:
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