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    Patent Pending

    BWH Egg Freezing Counseling Tool (EFCT)

    Predicts likelihood of live birth for elective egg freezing in women.

    IMPORTANT

    This calculator is not externally validated, and as such, should be used with caution.

    INSTRUCTIONS

    Use in women age 24–44 years undergoing fertility counseling.

    When to Use
    Pearls/Pitfalls
    Why Use

    Patients seeking fertility preservation with elective egg freezing.

    • Uses a woman’s age at egg retrieval and the number of mature eggs frozen to predict the probability of having at least one, two, or three live births.
    • Since limited data exist regarding live births following elective egg freezing, the BWH Egg Freezing Counseling Tool was developed from a surrogate population of presumably fertile women (egg donor, male-factor, and tubal-factor only infertility).
    • No number of frozen eggs can guarantee a live birth.
    • IVF stimulation cycles produce a variable number of eggs, even among women of similar ages. Older women typically obtain fewer eggs per stimulation cycle.
    • May be less reliable for women ≥39 years old.
    • May overestimate live birth rates for women undergoing non-elective egg freezing for medical reasons, such as cancer.
    • Data are retrospective and from a single academic institution in an insurance-mandated state.
    • Individual IVF clinics with different thaw survival and live birth rates may need to modify and customize this model.
    • Has yet to be prospectively validated.
    • Predicts likelihood of having at least one, two, or three live births using only two data points.
    • Incorporates likelihood that an embryo will have normal number of chromosomes.
    • Helps determine whether undergoing additional egg freezing cycles would result in a meaningful increase in likelihood of having a live birth.
    years
    eggs

    Result:

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    Next Steps
    Evidence
    Creator Insights
    Dr. Janis Fox

    About the Creator

    Janis H. Fox, MD, is an assistant professor in obstetrics, gynecology and reproductive biology at Harvard Medical School. She is also an attending reproductive endocrinologist in the Center for Infertility and Reproductive Surgery at Brigham and Women’s Hospital. Her clinical practice focuses primarily on infertility and assisted reproductive technologies. Dr. Fox has published on factors contributing to success and failure following in vitro fertilization.

    To view Dr. Janis Fox's publications, visit PubMed

    Dr. Randi Goldman

    About the Creator

    Randi Goldman, MD, is a clinical fellow in reproductive endocrinology and infertility at Brigham and Women's Hospital and Harvard Medical School. She completed her training in obstetrics and gynecology at Brigham and Women's Hospital/Massachusetts General Hospital and Harvard Medical School. Dr. Goldman’s primary research and clinical interests include reproductive health and the assessment and treatment of infertility.

    To view Dr. Randi Goldman's publications, visit PubMed

    Are you Dr. Randi Goldman? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    Content Contributors
    • Malinda Lee, MD
    About the Creator
    Dr. Janis Fox
    Dr. Randi Goldman
    Are you Dr. Randi Goldman?
    Content Contributors
    • Malinda Lee, MD