Hematopoietic Cell Transplantation-specific Comorbidity Index (HCT-CI)
Predicts survival after HCT in patients with hematologic malignancies, including optional age adjustment.
Entering age to obtain age-adjusted HCT-CI is optional. The original HCT-CI (without age adjustment) is still considered the standard.
When to Use
Afib/flutter, SSS, or ventricular arrhythmias+1
CAD, CHF, MI, or EF ≤50%+1
Valvular disease (except mitral prolapse)+3
Crohn disease or ulcerative colitis+1
None or diet-controlled0
Treated w/insulin or oral hypoglycemics+1
CVA or TIA+1
Depression or anxiety requiring psych consult or treatment+1
Chronic hepatitis (bilirubin >ULN to 1.5× ULN, or AST/ALT >ULN to 2.5× ULN)+1
Liver cirrhosis (bilirubin >1.5× ULN, or AST/ALT 2.5× ULN)+3
None or abx only on day 00
Requiring continuation of abx after day 0+1
SLE, RA, polymyositis, mixed CTD, or polymyalgia rheumatica+2
None or not requiring treatment0
None or serum Cr ≤2 mg/dL (177 µmol/L), not on dialysis, and no prior renal transplant0
Serum Cr >2 mg/dL (177 µmol/L), on dialysis, or prior renal transplant+2
None or mild0
DLco and/or FEV₁ 66%–80%, or dyspnea on slight activity+2
DLco and/or FEV1 ≤65% or dyspnea at rest or requiring oxygen+3
None or nonmelanoma skin cancer0
Treated at any point in the patient’s history+3
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- Michael Scordo, MD
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