Hematopoietic Cell Transplantation-specific Comorbidity Index (HCT-CI)
Predicts survival after HCT in patients with hematologic malignancies, including optional age adjustment.
INSTRUCTIONS
Entering age to obtain age-adjusted HCT-CI is optional. The original HCT-CI (without age adjustment) is still considered the standard.
When to Use
Pearls/Pitfalls
Why Use
None
0Afib/flutter, SSS, or ventricular arrhythmias
+1None
0CAD, CHF, MI, or EF ≤50%
+1Valvular disease (except mitral prolapse)
+3None
0Crohn disease or ulcerative colitis
+1None or diet-controlled
0Treated w/insulin or oral hypoglycemics
+1None
0CVA or TIA
+1None
0Depression or anxiety requiring psych consult or treatment
+1None
0Chronic hepatitis (bilirubin >ULN to 1.5× ULN, or AST/ALT >ULN to 2.5× ULN)
+1Liver cirrhosis (bilirubin >1.5× ULN, or AST/ALT 2.5× ULN)
+3No
0Yes
+1None or abx only on day 0
0Requiring continuation of abx after day 0
+1None
0SLE, RA, polymyositis, mixed CTD, or polymyalgia rheumatica
+2None or not requiring treatment
0Requiring treatment
+2None or serum Cr ≤2 mg/dL (177 µmol/L), not on dialysis, and no prior renal transplant
0Serum Cr >2 mg/dL (177 µmol/L), on dialysis, or prior renal transplant
+2None or mild
0DLco and/or FEV₁ 66%–80%, or dyspnea on slight activity
+2DLco and/or FEV1 ≤65% or dyspnea at rest or requiring oxygen
+3None or nonmelanoma skin cancer
0Treated at any point in the patient’s history
+3Allo-HCT
ASCT
Result:
Please fill out required fields.