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    Chief Complaint


    Organ System


    Patent Pending

    Cerebral Perfusion Pressure

    Calculates blood flow to the brain.


    Use in patients with an intracranial pressure monitoring device.

    When to Use
    Why Use

    Use in supine patients with elevated intracranial pressure (e.g. from hemorrhage, edema, mass).

    • Requires invasive intracranial pressure (ICP) monitoring.
    • Although there is still some debate in the literature, it is generally accepted that the normal range of CPP in a supine patient is 60–70 mmHg.
    • Clinicians must address both the patient’s CPP and ICP. For example, a patient could have a normal calculated CPP, but if the ICP is significantly elevated, it must be treated.
    • The definition of normal ICP changes with posture and age. It also varies slightly depending on which data are applied. Therefore, it is important to be aware of local practice guidelines when applying this calculator.
    • CPP decreases as ICP rises, leading to cerebral ischemia and further neurological injury.
    • Calculating CPP helps clinicians identify patients who may be experiencing ongoing neurological injury from inadequate cerebral perfusion.
    • Helps prevent further cerebral ischemia by treating elevated ICP and hypotension as appropriate.
    mm Hg
    mm Hg


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    Creator Insights
    Dr. Luzius A. Steiner

    About the Creator

    Luzius A. Steiner, MD, PhD, is a professor and the head of anesthesiology at University Hospital Basel in Switzerland. He has authored or co-authored dozens of studies in neurocritical care on cerebral perfusion pressure. Dr. Steiner is a member of the European Society of Intensive Care Medicine and the European Society of Anesthesiology.

    To view Dr. Luzius A. Steiner's publications, visit PubMed

    Are you Dr. Luzius A. Steiner? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    Content Contributors
    • Lubabah Ben-Ghaly, MD
    About the Creator
    Dr. Luzius A. Steiner
    Are you Dr. Luzius A. Steiner?
    Content Contributors
    • Lubabah Ben-Ghaly, MD