Lapostolle F, Borron SW, Verdier C, Taboulet P, Guerrier G, Adnet F, Clemessy JL, Bismuth C, Baud FJ. Digoxin-specific Fab fragments as single first-line therapy in digitalis poisoning. Crit Care Med. 2008 Nov;36(11):3014-8. doi: 10.1097/CCM.0b013e31818b341c.

Antman EM, Wenger TL, Butler VP Jr, Haber E, Smith TW. Treatment of 150 cases of Life-Threatening Digitalis Intoxication With Digoxin-Specific Fab Antibody Fragments: Final Report of a Multicenter Study. Circulation. 1990;81:1744-52.

Bismuth C, Gaultier M, Conso F, Efthymiou ML. Hyperkalemia in Acute Digitalis Poisoning: Prognostic Significance and Therapeutic Implications. Clin Toxicol. 1973;6(2):153-62.

Digibind® Injection Information, Manufacturer's Guidelines

Hack JB. Cardioactive Steroids. In: Hoffman R, Howland MA, Lewin N et al. Goldfrank's Toxicologic Emergencies, Tenth Edition. McGraw-Hill Education / Medical; 2014.

Howland MA. Digoxin-Specific Antibody Fragments. In: Hoffman R, Howland MA, Lewin N et al. Goldfrank's Toxicologic Emergencies, Tenth Edition. McGraw-Hill Education / Medical; 2014.

Dr. Frédéric Lapostolle

DigiFab (Digibind) Dosing for Digoxin Poisoning

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weight

amount

Doses DigiFab in patients with confirmed digoxin poisoning or overdose.

DigiFab dosing for digoxin toxicity.

DigiFab (Digibind) Dosing

Scott Lucyk, MD, is an emergency physician and medical toxicologist with the Poison and Drug Information Service (PADIS) in Calgary, Alberta, Canada. Dr. Lucyk obtained his Fellowship of the Royal College of Physicians of Canada (FRCPC) in emergency medicine from the University of Alberta, followed by a fellowship in medical toxicology at the New York Poison Control Center in New York City. Currently, he is the associate medical director at PADIS and the program director of the clinical pharmacology and toxicology subspecialty in Calgary. Dr. Lucyk focuses his non-clinical time on medical education and resident teaching.

Scott Lucyk, MD

The DigiFab Dosing calculator doses DigiFab in patients with confirmed digoxin poisoning or overdose.

Serum digoxin level

Weight

Amount digoxin ingested

Morphine Milligram Equivalents

ABG Analysis

Estimated Serum Concentration of Alcohols

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