MDCalc

Fomepizole Dosing

Doses fomepizole for methanol and ethylene glycol reversal.

Diagnostic Result

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Advice

If a patient has an unexplained anion gap or osmolar gap, resuscitate the patient with fluids and thiamine, with or without glucose (food or IV dextrose) and repeat the BMP and osmolar gap in an hour. If anion gap worsens, consider toxic alcohol ingestion.

Management

Relationship between osmolar gap and anion gap in toxic alcohol:
Relationship between osmolar gap and anion gap in toxic alcohol.