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    Patent Pending

    Sodium Correction Rate in Hyponatremia and Hypernatremia

    Calculates recommended fluid type, rate, and volume to correct hyponatremia slowly (or more rapidly if seizing).


    This dosing tool is intended to assist with calculation, not to provide comprehensive or definitive drug information. Always double-check dosing of any drug and consult a pharmacist when necessary.

    When to Use

    Use with the Sodium Deficit in Hyponatremia calculator which estimates the total amount of sodium that needs to be replaced.

    • The proper rate of correction of hyponatremia is important.

    • Overly rapid correction, particularly in chronic hyponatremia, can lead to osmotic demylination syndrome (ODS), previously known as central pontine myelinolysis (CPM).

    • In most cases, sodium correction should be done in an ICU setting, especially with hypertonic fluids for replacement.



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    Creator Insights
    Dr. Nicolaos E. Madias

    About the Creator

    Nicolaos E. Madias, MD, is the chair of the department of medicine at the St. Elizabeth's Medical Center in Boston, Massachusetts. He is also a professor of medicine, specializing in Nephrology, at the Tufts University School of Medicine. Dr. Madias has co-authored over 100 articles published in peer reviewed journals.

    To view Dr. Nicolaos E. Madias's publications, visit PubMed

    Are you Dr. Nicolaos E. Madias? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    About the Creator
    Dr. Nicolaos E. Madias
    Are you Dr. Nicolaos E. Madias?