Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm

    Disease

    Select...

    Specialty

    Select...

    Chief Complaint

    Select...

    Organ System

    Select...

    Patent Pending

    Save your unit preferences in settings!

    Dutch Criteria for Familial Hypercholesterolemia (FH)

    Diagnoses familial hypercholesterolemia (FH) based on clinical, genetic and family history.
    Favorite
    When to Use
    Pearls/Pitfalls
    Why Use

    Patients with suspected familial hypercholesterolemia (FH), including those with elevated cholesterol and/or family history of premature cardiac events.

    • Assigns points to risk factors and stratifies likelihood of diagnosis into one of four categories: definite, probable, possible, and unlikely.
    • Requires DNA testing for completeness.
    • FH is underdiagnosed and carries significant mortality risk from cardiac events.
    • The European Atherosclerosis Society recommends that the Dutch Criteria be used to diagnose FH.
    • Alternative diagnostic criteria include US MEDPED and the Simon Broome Diagnostic Criteria. The risk factors in each criteria set are similar, and clinical judgment as well as local practice factors (similarity of target population to study population) should be considered.
    Entry Criterion

    If yes, 9+ additional criteria required for Definite FH

    No
    Yes

    Diagnostic Result:

    Please fill out required fields.

    Next Steps
    Evidence
    Creator Insights

    Advice

    Consider lifestyle changes, drug therapy, family testing, and other measures to manage FH if diagnosed.

    About the Creator
    Dr. Melissa Austin
    Are you Dr. Melissa Austin?