 Critical Issues in the Evaluation and Management of Adult Patients With Suspected Acute Nontraumatic Thoracic Aortic Dissection

Official 2014 guideline from the American College of Emergency Physicians.

 Critical Issues in the Evaluation of Adult Patients With Suspected Transient Ischemic Attack in the Emergency Department

Official 2016 guideline from the American College of Emergency Physicians.

 Critical Issues in the Initial Evaluation and Management of Patients Presenting to the Emergency Department in Early Pregnancy

Clinical Policy for Well-Appearing Infants and Children Younger Than 2 Years of Age Presenting to the Emergency Department With Fever

Critical Issues Related to Opioids in Adult Patients Presenting to the Emergency Department

Official 2020 guideline from the American College of Emergency Physicians.

Official 2020 guideline from ACEP.

Critical Issues in the Diagnosis and Management of the Adult Psychiatric Patient in the Emergency Department

Official 2017 guideline from the American College of Emergency Physicians.

Critical Issues in the Evaluation and Management of Adult Out-of-Hospital or Emergency Department Patients Presenting With Severe Agitation

Official 2023 guideline for severe agitation from the American College of Emergency Physicians.

Based on 2023 guideline for severe agitation from ACEP.

Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Carbon Monoxide Poisoning

Official 2025 guideline from the American College of Emergency Physicians.

Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Headache

Official 2019 guideline from the American College of Emergency Physicians.

Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Heart Failure Syndromes

Official 2022 guideline from the American College of Emergency Physicians.

Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Suspected Acute Venous Thromboembolic Disease

Official 2018 guideline from the American College of Emergency Physicians.

Critical Issues in the Evaluation and Management of Adult Patients in the Emergency Department With Asymptomatic Elevated Blood Pressure

Official 2013 guideline from the American College of Emergency Physicians.

Critical Issues in the Evaluation and Management of Emergency Department Patients With Suspected Appendicitis

Official 2023 guideline from the American College of Emergency Physicians.

Official 2023 guideline from ACEP.

Critical Issues in the Evaluation and Management of Emergency Department Patients With Suspected Non-ST-Elevation Acute Coronary Syndromes

Official 2018 guideline from ACEP.

Critical Issues in the Evaluation of Adult Patients Presenting to the Emergency Department With Acute Blunt Trauma

Based on 2024 guideline for acute blunt trauma from the American College of Emergency Physicians.

Based on 2024 guideline for blunt trauma from ACEP.

Critical Issues in the Management of Adult Patients Presenting to the Emergency Department With Community-Acquired Pneumonia

Critical Issues in the Management of Adult Patients Presenting to the Emergency Department With Mild Traumatic Brain Injury

Critical Issues in the Management of Adult Patients Presenting to the Emergency Department With Seizures

Official 2024 guideline from the American College of Emergency Physicians.

Official 2024 guideline from ACEP.

Critical Issues in the Outpatient Management of Adult Patients Presenting to the Emergency Department With Asymptomatic Elevated Blood Pressure

Official 2025 Guideline from the American College of Emergency Physicians.

2025 ACEP Guideline for Outpatient Asymptomatic Elevated BP.

Emergency Department Management of Patients Needing Reperfusion Therapy for Acute ST-Segment Elevation Myocardial Infarction

Procedural Sedation and Analgesia in the Emergency Department

Use of Thrombolytics for the Management of Acute Ischemic Stroke in the Emergency Department

Acute-on-Chronic Liver Failure

Official guideline from the American College of Gastroenterology.

Alcoholic Liver Disease

Chronic Pancreatitis

Clinical Use of Esophageal Physiologic Testing

Official guideline of the American College of Gastroenterology.

Colorectal Cancer Screening 2021

Diagnosis and Management of Achalasia

Diagnosis and Management of Barrett’s Esophagus

Official guideline from the American College of Gastroenterology.
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Diagnosis and Management of Celiac Disease

Official 2023 guideline of the American College of Gastroenterology.

Diagnosis and Management of Eosinophilic Esophagitis (EoE)

Official 2025 guideline from the American College of Gastroenterology.

Diagnosis and Management of Gastroesophageal Reflux Disease

Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

Diagnosis and Management of Pancreatic Cysts

Diagnosis and Management of Small Bowel Bleeding

Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults

Disorders of the Hepatic and Mesenteric Circulation

Epidemiology, Risk Factors, Patterns of Presentation, Diagnosis, and Management of Colon Ischemia (CI)

Evaluation of Abnormal Liver Chemistries

Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes

Guidelines for Diagnosis, Treatment, and Prevention of Clostridium difficile Infections

Official guideline from the American College of Gastroenterology, updated June 2021.

Hereditary Hemochromatosis

Liver Disease and Pregnancy

Management of Acute Pancreatitis

Official 2024 guideline from the American College of Gastroenterology.

Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period

Management of Crohn’s Disease in Adults

Management of Dyspepsia

Management of Gastroparesis

Management of Irritable Bowel Syndrome

Management of Patients With Acute Lower Gastrointestinal Bleeding

Nutrition Therapy in the Adult Hospitalized Patient

Preventive Care in Inflammatory Bowel Disease

Primary Sclerosing Cholangitis

Small Intestinal Bacterial Overgrowth

The Diagnosis and Management of Focal Liver Lesions

Treatment of Helicobacter pylori Infection

Ulcerative Colitis in Adults

Updated Diagnosis and Management of Barrett’s Esophagus

Upper Gastrointestinal and Ulcer Bleeding

Official guideline from the American College of Gastroenterology, updated May 2021.

Clinical Practice Guideline on Pharmacological Management of Moderate-to-Severe Ulcerative Colitis

2024 Clinical Practice Guideline from the American Gastroenterological Association.

Gastrointestinal Evaluation of Iron Deficiency Anemia

Based on guidelines from the American Gastroenterological Association.

Initial Management of Acute Pancreatitis

Laboratory Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults (IBS-D)

Based on guidelines from the American Gastroenterological Association. Use to evaluate an immunocompetent patient with complaints of "watery" diarrhea of at least 4 weeks duration.

Management of Acute Diverticulitis

Medical Management of Microscopic Colitis

Pharmacological Management of Irritable Bowel Syndrome With Constipation (IBS-C)

Based on guidelines from the American Gastroenterological Association. Expert content provided by Morgan Allyn Sendzischew Shane, MD, MSCTI.

Pharmacological Management of Irritable Bowel Syndrome With Diarrhea (IBS-D)

Prevention and Treatment of Hepatitis B Virus Reactivation (HBVr) in At-Risk Individuals

2025 Guideline from the American Gastroenterological Association for Hepatits B Virus Reactivation.

Adjuvant Endocrine Therapy for Women With Hormone Receptor-positive Breast Cancer

Based on guidelines from the American Society of Clinical Oncology.

Adjuvant Systemic Therapy and Adjuvant Radiation Therapy for Stages I-IIIA Completely Resected Non-small Cell Lung Cancers

Based on guidelines from the American Society of Clinical Oncology and Cancer Care Ontario.

Adjuvant Therapy for Resected Biliary Tract Cancer

Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors

Based on guidelines from the Congress of Neurological Surgeons, also endorsed by <abbr title="American Society of Clinical Oncology">ASCO</abbr> and <abbr title="Society for Neuro-Oncology">SNO</abbr>.

Chemotherapy and Targeted Therapy for Women with HER2-negative (or unknown) Advanced Breast Cancer

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Clinically Localized Prostate Cancer

Based on guidelines from <abbr title="American Urological Association">AUA</abbr>, <abbr title="American Society for Radiation Oncology">ASTRO</abbr>, and <abbr title="Society of Urologic Oncology">SUO</abbr>, also endorsed by <abbr title="American Society of Clinical Oncology">ASCO</abbr>.

Based on guidelines from AUA, ASTRO, and SUO.

Definitive and Adjuvant Radiotherapy in Locally Advanced Non-Small Cell Lung Cancer (LA NSCLC)

Based on guidelines from the American Society for Radiation Oncology, also endorsed by ASCO.

Diabetes Care in the Hospital

Based on guidelines from the American Diabetes Association.

Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza

Based on guidelines from the Infectious Diseases Society of America.

Duration of Oxaliplatin-Containing Adjuvant Therapy for Stage III Colon Cancer

Based on guidelines from the American Society of Clinical Oncology.

Hereditary Colorectal Cancer Syndromes

Based on guidelines from the European Society for Medical Oncology, also endorsed by ASCO.

Initial Diagnostic Work-Up of Acute Leukemia

Based on guidelines from <abbr title="College of American Pathologists">CAP</abbr> and <abbr title="American Society of Hematology">ASH</abbr>, also endorsed by <abbr title="American Society of Clinical Oncology">ASCO</abbr>.

Management of Asymptomatic Bacteriuria (ASB)

Management of Blood Cholesterol

Based on guidelines from the American College of Cardiology and the American Heart Association Task Force.

Based on guidelines from the ACC and AHA Task Force.

Management of Small Renal Masses

Management of the Neck in Squamous Cell Carcinoma of the Oral Cavity and Oropharynx

Muscle-Invasive and Metastatic Bladder Cancer

Based on 2023 guidelines from the European Association of Urology.

Neoadjuvant Chemotherapy for Newly Diagnosed, Advanced Ovarian Cancer

Based on guidelines from <abbr title="Society of Gynecologic Oncology">SUO</abbr> and <abbr title="American Society of Clinical Oncology">ASCO</abbr>.

Postoperative Radiation Therapy for Endometrial Cancer

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Potentially Curable Pancreatic Adenocarcinoma

Primary Prevention of Cardiovascular Disease (CVD)

Based on guidelines from the American College of Cardiology and the American Heart Association.

Based on guidelines from the ACC and AHA.

Radiation Therapy for Glioblastoma

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Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma (OPSCC)

Renal Mass and Localized Renal Cancer

Based on guidelines from the American Urological Association.

Role of Bone-modifying Agents in Multiple Myeloma

Screening for Breast Cancer in Average-Risk Women

Based on 2019 guidelines from the American College of Physicians.

Based on 2019 guidelines from ACP.

Sentinel Lymph Node Biopsy for Melanoma

<span data-sheets-value="{&quot;1&quot;:2,&quot;2&quot;:&quot;Based on guidelines from the American Society of Clinical Oncology and the Society of Surgical Oncology.&quot;}" data-sheets-userformat="{&quot;2&quot;:641,&quot;3&quot;:{&quot;1&quot;:0},&quot;10&quot;:2,&quot;12&quot;:0}">Based on guidelines from the American Society of Clinical Oncology and the Society of Surgical Oncology.

Stereotactic Body Radiotherapy (SBRT) for Early-Stage Non-small Cell Lung Cancer (NSCLC)

Tonsillectomy in Children

Based on guidelines from the American Academy of Otolaryngology-Head and Neck Surgery Foundation.

Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

Based on guidelines from the American College of Rheumatology.

Treatment of Hepatocellular Carcinoma

Based on guidelines from the American Association for the Study of Liver Diseases.

Treatment of Malignant Pleural Mesothelioma

Treatment of Multiple Myeloma

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Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer

Based on guidelines from <abbr title="American Urological Association">AUA</abbr>, <abbr title="American Society of Clinical Oncology">ASCO</abbr>, <abbr title="American Society for Radiation Oncology">ASTRO</abbr>, and <abbr title="Society of Urologic Oncology">SUO</abbr>.

Based on guidelines from AUA, ASCO, ASTRO, and SUO.

Treatment of Psoriatic Arthritis

Based on guidelines from the American College of Rheumatology.
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Treatment of Rheumatoid Arthritis

Treatment of Small-cell Lung Cancer (SCLC)

Based on guidelines from the American College of Chest Physicians, also endorsed by ASCO.

Calc Function

Guideline Summaries