Karnofsky Performance Status Scale
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The Karnofsky Performance Status Scale is clearly useful to clinicians, and either this or another functional status scale should be used to improve understanding of patient needs and abilities, as well as potentially to prognose.
We are unaware of validated management algorithms using the Karnofsky Scale.
The Karnofsky Scale and other performance scales should be used in the holistic assessment of cancer patients, though its accuracy as a prognostic tool in individual cases is not yet well proved.