The Manning Criteria were developed to help predict which patients will de diagnosed with IBS, i.e. will not have any organic disease identified after complete work-up. In a setting where work-up resources are limited, or take undue time, these may be particularly useful.
We are unaware of validated management algorithms using the Manning Criteria.
IBS is a ‘rule-out’ diagnosis, which is to say all other possibilities must be ruled out first.