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      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm





    Chief Complaint


    Organ System


    Patent Pending

    Manning Criteria for Diagnosis of Irritable Bowel Syndrome (IBS)

    Determines likelihood of irritable bowel syndrome diagnosis based on clinically significant criteria.
    When to Use
    Why Use

    Patients being evaluated for possible IBS.

    • The Manning Criteria were developed through patient survey and follow-up.
    • They differentiate patients with organic and non-IBS conditions.

    Points to keep in mind:

    • Studies have found highly variable diagnostic performance of the criteria.

    The symptoms that define IBS are subjective and self-reported, making a diagnostic classification system helpful. Moreover, there is evidence to support the notion that patients meeting criteria may be more likely to respond to some therapies.

    3+ required for positive diagnosis (and 0 red flags)

    Red Flag Signs

    If any are present, IBS is not likely

    Diagnostic Result:

    Please fill out required fields.

    Next Steps
    Creator Insights


    The Manning Criteria were developed to help predict which patients will de diagnosed with IBS, i.e. will not have any organic disease identified after complete work-up. In a setting where work-up resources are limited, or take undue time, these may be particularly useful.


    We are unaware of validated management algorithms using the Manning Criteria.

    Critical Actions

    IBS is a ‘rule-out’ diagnosis, which is to say all other possibilities must be ruled out first.

    About the Creator
    Dr. A. P. Manning
    Are you Dr. A. P. Manning?