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      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm

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    Patent Pending

    Memorial Sloan-Kettering Cancer Center (MSKCC/Motzer) Score for Metastatic Renal Cell Carcinoma (RCC)

    Predicts survival based on clinical and laboratory data in metastatic RCC patients.

    INSTRUCTIONS

    • Use baseline factors at the start date of the current line of systemic therapy, except for the “time of diagnosis to systemic therapy” criterion, which is always relative to first-line therapy.

    • Always correct calcium concentration for low albumin before scoring.

    When to Use
    Pearls/Pitfalls
    Why Use

    Patients with metastatic RCC undergoing systemic therapy and being considered for clinical trial enrollment, and in clinical practice for the estimation of prognosis.

    • May assist in estimating prognosis of patients with metastatic RCC, but is not currently used for making decisions about treatment (use IMDC Risk Model instead).

    • Easy to use and uses readily available clinical and laboratory variables.

    Assists clinicians in discussions about prognosis for patients with metastatic RCC and can be used as a stratification factor in clinical trials.

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    Result:

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    Next Steps
    Evidence
    Creator Insights
    Dr. Robert J. Motzer

    About the Creator

    Robert J. Motzer, MD, is a medical oncologist at Memorial Sloan Kettering Cancer Center. He received the Career Development Award from the National Institutes of Health and the Schonfeld Award from the Kidney Cancer Association. Dr. Motzer’s research focuses on renal cell carcinoma, germ-cell tumors, and bone marrow and blood cell transplantation.

    To view Dr. Robert J. Motzer's publications, visit PubMed

    Are you Dr. Robert J. Motzer? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    Content Contributors
    Reviewed By
    • Toni Choueiri, MD
    About the Creator
    Dr. Robert J. Motzer
    Are you Dr. Robert J. Motzer?
    Content Contributors
    Reviewed By
    • Toni Choueiri, MD