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    Reynolds Risk Score for Cardiovascular Risk in Women

    Estimates 10-year cardiovascular risk in women over age 45 years.
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    When to Use
    Pearls/Pitfalls
    Why Use

    Women over age 45.

    • The Reynolds Risk Score estimates risk of adverse cardiovascular event (ischemic stroke, myocardial infarction, need for coronary revascularization, or cardiovascular death) in women over age 45.
    • Derivation study included mostly white women of middle class socioeconomic range, and caution should be used if generalizing to non-white women.
    • The study also did not shed new light on cardiovascular risk in very low risk women (<5% risk over ten years).
    • hsCRP level is not often ordered in routine outpatient laboratory tests.
    • May help determine need for statin therapy for risk reduction. Women with a Reynolds Risk score of 10% or less over a ten year period generally do not require statin therapy.
    • Re-classifies 40-50% of women previously in the intermediate cardiovascular range to lower or higher risk categories compared to prior studies, like the Framingham Coronary Heart Disease Risk Score, conducted in mostly Caucasian male patients.
    years
    mm Hg
    No
    Yes
    No
    Yes
    mg/dL
    mg/dL
    mg/L
    No
    Yes

    Result:

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    Next Steps
    Evidence
    Creator Insights

    Advice

    • Should be used in conjunction with detailed history and physical to aid in identifying female patients who may benefit from statin therapy.
    • Should incorporate clinical judgment when determining a patient's risk for cardiovascular events and benefit of intervention.
    Content Contributors
    • Emma Oberlander, DO
    Reviewed By
    • Jessica Bloom-Foster, MD
    About the Creator
    Dr. Paul M. Ridker
    Are you Dr. Paul M. Ridker?
    Content Contributors
    • Emma Oberlander, DO
    Reviewed By
    • Jessica Bloom-Foster, MD