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      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm





    Chief Complaint


    Organ System


    Patent Pending

    Rome III Diagnostic Criteria for Irritable Bowel Syndrome (IBS)

    Provides criteria for diagnosis of irritable bowel syndrome (IBS) within 12 week period.


    Recurrent abdominal pain or discomfort, 3 days per month in the last 3 months (12 weeks), associated with ≥2 of the criteria below. The criteria are fulfilled with symptoms onset 6 months prior to diagnosis.
    When to Use
    Why Use

    Patients being evaluated for possible IBS.

    • The Rome III criteria help diagnose irritable bowel syndrome (IBS).

    Points to keep in mind:

    • There remains no objective reference (i.e. ‘gold’) standard for IBS; the criteria were developed through a literature review and consensus process.

    The symptoms that define IBS are subjective and self-reported, making a classification system helpful. Moreover, there is evidence to support the notion that patients who meet formal Rome criteria may be more likely to respond to certain therapies.

    2+ required for positive diagnosis

    Diagnostic Result:

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    Next Steps
    Creator Insights


    The Rome III criteria are helpful in classifying patients and for determining potential therapies.


    We are unaware of validated management algorithms using the Rome criteria.

    Critical Actions

    IBS is a ‘rule-out’ diagnosis, which is to say all other possibilities must be ruled out first.

    Content Contributors
    • Ahmad Khan, MD
    About the Creator
    Dr. Douglas Drossman
    Are you Dr. Douglas Drossman?
    Content Contributors
    • Ahmad Khan, MD