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      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm





    Chief Complaint


    Organ System


    Patent Pending

    Acute Decompensated Heart Failure National Registry (ADHERE) Algorithm

    Predicts in-hospital mortality in patients with heart failure (HF).
    When to Use
    Why Use

    Inpatients with acute decompensated heart failure.

    • The ADHERE Algorithm estimates in-hospital mortality in admitted patients with acute decompensated HF.
    • This model uses 3 variables (BUN, SBP, creatinine) to classify patients, but it does not allow more precise characterization of individual risk.
    • The ADHERE Algorithm can NOT predict intermediate- and long-term mortality risks.
    • The analysis of the ADHERE cohort also identified heart rate and age as significant independent predictors of risk according to the regression model, but these variables were omitted from the algorithm in order to simplify the model as a bedside tool.
    • The data used reflect individual hospitalization episodes, not individual patients, and multiple hospitalizations of the same patient may be entered into the registry as separate records.
    • Study results were based on a registry, the accuracy of which can be influenced by differences in disease assessment, treatment, and documentation patterns at participating institutions.

    Risk stratification, triage and optimization of medical management.



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    Next Steps
    Creator Insights


    • If the algorithm identifies the patient to be high risk, early consultation to cardiology is crucial to appropriately treat these patients and reduce risk of readmission.
    • Appropriate planning and care coordination between multidisciplinary teams, and early and frequent follow-up in the cardiologist’s office is essential.
    • Evidence-based guideline directed medical therapy is meant to be used for both high and low risk patients with CHF. However, in the era of resource constraints, these limited resources may not be allocated to low risk patients.
    Content Contributors
    Reviewed By
    • Vijay Shetty, MBBS
    About the Creator
    Dr. Gregg Fonarow
    Content Contributors
    Reviewed By
    • Vijay Shetty, MBBS