Wolf SJ, Mccubbin TR, Nordenholz KE, Naviaux NW, Haukoos JS. Assessment of the pulmonary embolism rule-out criteria rule for evaluation of suspected pulmonary embolism in the emergency department. Am J Emerg Med. 2008;26(2):181-5.

Kline JA, et al. Clinical criteria to prevent unnecessary diagnostic testing in emergency department patients with suspected pulmonary embolism. J Thromb Haemost 2004; 2: 1247–55.

Kline JA, et al. Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost 2008; 6: 772–80.

Madsen T, Jedick R, Teeples T, Carlson M, Steenblik J. Impact of altitude-adjusted hypoxia on the Pulmonary Embolism Rule-out Criteria. Am J Emerg Med. 2019;37(2):281-285.

Dr. Jeffrey Kline

Dr. Stephen J. Wolf

Altitude-Adjusted PERC Rule

altitude

lowo2

higho2

leg_swelling

hemoptysis

trauma

dvt_pe_history

estrogen

Rules out PE if no criteria are present; includes SaO2 adjustment for altitude.

Benjamin H. Slovis, MD, MA, is an emergency medicine physician and informatician in the department of emergency medicine at Thomas Jefferson University in Philadelphia. A native of New Jersey, Dr. Slovis attended Cornell University for his undergraduate studies and received his MD from UMDNJ–Robert Wood Johnson Medical School. He completed his residency at the Icahn School of Medicine at Mount Sinai and a National Library of Medicine Post-Doctoral Research Fellowship with a masters degree from the department of Biomedical Informatics at Columbia University. His research interests include clinical decision support systems, health-information exchange, and medical education.

Benjamin Slovis, MD

Stephen Jenkins, MD, is a clinical instructor in the Division of Internal Medicine at the University of Utah. He is also the director of the University of Utah's Thrombosis Service. Dr. Jenkin's primary research interests include transitions of care for the acutely ill and thrombosis patients.

Stephen Jenkins, MD

The Altitude-adjusted PERC Rule for Pulmonary Embolism rules out PE if no criteria are present; includes SaO₂ adjustment for altitude. 

PERC Rule

Age-Adjusted D-dimer

4PEPS Score for PE

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Calc Function