Immune-Related Adverse Events for Endocrine Toxicities - Hypothyroidism
Grades severity of hypothyroidism secondary to immune checkpoint inhibitor therapy.
Use in adult patients with symptoms of hypothyroidism and/or abnormalities of TSH or free thyroxine level that developed while on treatment with immune checkpoint inhibitors.
When to Use
TSH <10 mIU/L and asymptomatic
Moderate symptoms; able to perform ADLs; TSH persistently >10 mIU/L
Severe symptoms, medically significant or life-threatening consequences, unable to perform ADLs
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- Nazli Dizman, MD
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