tPA Contraindications for Ischemic Stroke
Provides inclusion/exclusion criteria when deciding to use tPA on a patient with acute ischemic stroke.
INSTRUCTIONS
Institutions may have slightly different absolute and relative contraindications to Tissue Plasminogen Activator (tPA); this list is meant to be a quick reference, but practice should be guided by institutional protocol and consultation with neurology. Reflects recommendations from Demaerschalk et al, Stroke 2015.
When to Use
Pearls/Pitfalls
Why Use
Eligibility for tPA
No
Yes
No
Yes
No
Yes
Absolute Contraindications to tPA
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
Relative Contraindications/Warnings to tPA
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
Additional Warnings to tPA >3hr Onset
No
Yes
No
Yes
No
Yes
No
Yes
No
Yes
Result:
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