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      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
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    Attention COACH STUDY participants:

    The principal investigators of the study request that you use the official version of the modified score here.

    Reynolds Risk Score for Cardiovascular Risk in Women

    Estimates 10-year cardiovascular risk in women over age 45 years.
    When to Use
    Pearls/Pitfalls
    Why Use

    Women over age 45.

    • The Reynolds Risk Score estimates risk of adverse cardiovascular event (ischemic stroke, myocardial infarction, need for coronary revascularization, or cardiovascular death) in women over age 45.
    • Derivation study included mostly white women of middle class socioeconomic range, and caution should be used if generalizing to non-white women.
    • The study also did not shed new light on cardiovascular risk in very low risk women (<5% risk over ten years).
    • hsCRP level is not often ordered in routine outpatient laboratory tests.
    • May help determine need for statin therapy for risk reduction. Women with a Reynolds Risk score of 10% or less over a ten year period generally do not require statin therapy.
    • Re-classifies 40-50% of women previously in the intermediate cardiovascular range to lower or higher risk categories compared to prior studies, like the Framingham Coronary Heart Disease Risk Score, conducted in mostly Caucasian male patients.
    years
    mm Hg
    No
    Yes
    No
    Yes
    mg/dL
    mg/dL
    mg/L
    No
    Yes

    Result:

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    Evidence
    Creator Insights
    Dr. Paul M. Ridker

    About the Creator

    Paul M. Ridker, MD, MPH, is the Eugene Braunwald Professor of Medicine at Harvard Medical School and directs the Center for Cardiovascular Disease Prevention, a translational research unit at the Brigham and Women’s Hospital in Boston. He is also a practicing cardiologist at the Brigham and Women’s Hospital and an echocardiographer by sub-specialty training. Dr. Ridker’s research focuses on the design and conduct of multi-national randomized trials, the development of inflammatory biomarkers for clinical and research use, the molecular and genetic epidemiology of cardiovascular diseases, and novel strategies for cardiovascular disease detection and prevention.

    To view Dr. Paul M. Ridker's publications, visit PubMed

    Are you Dr. Paul M. Ridker? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
    Content Contributors
    • Emma Oberlander, DO
    Reviewed By
    • Jessica Bloom-Foster, MD
    About the Creator
    Dr. Paul M. Ridker
    Are you Dr. Paul M. Ridker?
    Content Contributors
    • Emma Oberlander, DO
    Reviewed By
    • Jessica Bloom-Foster, MD