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      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm





    Chief Complaint


    Organ System


    Patent Pending

    GALAD Model for Hepatocellular Carcinoma (HCC)

    Diagnoses HCC based on serum biomarkers in patients with chronic liver disease (CLD).
    When to Use
    Why Use

    Use in patients with chronic liver disease (CLD).

    • Estimates risk that a CLD patient has HCC using only tumor markers and demographics (i.e., no imaging).
    • AUROC was 0.92 in one validation study (Best 2016).


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    Next Steps
    Creator Insights
    Dr. Philip J. Johnson

    About the Creator

    Philip J. Johnson, MD, FRCP, is a professor in translational oncology at the University of Liverpool. He is also the deputy director of the North West Cancer Research Centre, University of Liverpool. Dr. Johnson’s primary research is focused on diagnosis and prognosis of hepatobiliary and pancreatic cancer.

    To view Dr. Philip J. Johnson's publications, visit PubMed

    Are you Dr. Philip J. Johnson? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
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