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    Patent Pending

    Glasgow-Imrie Criteria for Severity of Acute Pancreatitis

    Determines severity of pancreatitis based on 8 laboratory values.
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    INSTRUCTIONS

    These criteria are traditionally scored with values at 48 hours after admission.
    When to Use
    Pearls/Pitfalls
    Why Use

    Patients with acute pancreatitis.

    • The Glasgow-Imrie Criteria predict severity of pancreatitis but at 48 hours after admission.
    • A severe pancreatitis episode involved death, need for surgery or complications from pancreatitis.

    Points to keep in mind:

    • The lab values are usually evaluated at 48 hours after admission, not upon admission.
    • This study was developed in the 1980s, prior to significant advances in the treatment and evaluation of pancreatitis, including advanced imaging.

    Predicting severity, mortality, and need for therapies in pancreatitis is notoriously difficult and multifactorial. Using a scoring system may help standardize treatment and allow for targeting patients in greatest danger.

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    Result:

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    Next Steps
    Evidence
    Creator Insights

    Advice

    The Glasgow-Imrie Criteria are comparable to the Ranson's criteria, but both have a disadvantage of requiring a 48 hours delay before they can be appropriately applied. Studies have suggested a binary cutoff at ≥3 as suggesting a significant increase in likelihood of severe pancreatitis.

    Management

    Local management algorithms using the criteria have been published; none are validated.

    Critical Actions

    The Glasgow-Imrie Criteria require using peak laboratory values and can be appropriately applied only at 48 hours after admission.

    About the Creator
    Dr. Clem Imrie
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