Treatment of Hepatocellular Carcinoma(beta)
AASLD recommends surveillance of adults with cirrhosis because it improves overall survival.
AASLD suggests surveillance using ultrasound (US), with or without alpha-fetoprotein (AFP), every 6 months.
AASLD suggests several options for diagnosis in patients with cirrhosis and an indeterminate nodule, including follow-up imaging, imaging with an alternative modality or alternative contrast agent, or biopsy, but cannot recommend one option over the other.
AASLD suggests bridging to transplant in patients listed for liver transplantation within OPTN T2 (Milan) criteria to decrease progression of disease and subsequent dropout from the waiting list.
AASLD recommends LRT over no treatment in adults with cirrhosis and HCC (T2 or T3, no vascular involvement) who are not candidates for resection or transplantation.
How strong is the AASLD's recommendation?