Calc Function

  • Diagnosis
  • Rule Out
  • Prognosis
  • Formula
  • Treatment
  • Algorithm
  • Disease
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    Specialty
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    Chief Complaint
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    Organ System
    Select...

    Postoperative Radiation Therapy for Endometrial Cancer

    Based on guidelines from the American Society for Radiation Oncology, also endorsed by ASCO.

    Treatment

    Hysterectomy

    Strong recommendation
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    Low quality evidence

    Strong recommendation
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    High quality evidence

    Hysterectomy and Vaginal Cuff Brachytherapy

    Strong recommendation
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    Low quality evidence

    Strong recommendation
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    Moderate quality evidence

    Vaginal Cuff Brachytherapy

    Strong recommendation
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    Moderate quality evidence

    Strong recommendation
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    Low quality evidence

    Postoperative External Beam Radiation

    Strong recommendation
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    High quality evidence

    Strong recommendation
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    High quality evidence

    Strong recommendation
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    Moderate quality evidence

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    Moderate quality evidence

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    Low quality evidence

    Brachytherapy and External Beam Radiation

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    Low quality evidence

    Management

    Integration of Radiation Therapy and Chemotherapy

    Strong recommendation
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    Moderate quality evidence

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    Low quality evidence

    How strong is the ASTRO's recommendation?

    Strong recommendation
    Evidence suggests that the benefit of the intervention outweighs the risk, and the panel has reached uniform consensus.
    Evidence suggests that the benefit of the intervention equals the risk, or vice versa, and the panel has reached uniform or nonuniform consensus.
    High quality evidence
    Evidence is considered high quality when it is obtained from 1 or more well-designed and well-executed randomized, controlled trials (RCTs) that yield consistent and directly applicable results. Further research is very unlikely to change our confidence in the estimate of effect.
    Moderate quality evidence
    Evidence is considered moderate quality when it is obtained from RCTs with important limitations. Further research will probably have an important effect on our confidence in the estimate of effect and may change the estimate.
    Low quality evidence
    Evidence obtained from observational studies would typically be rated as low quality because of the risk for bias. Further research is very likely to have an important effect on our confidence in the estimate of effect and will probably change the estimate.