Calc Function

  • Diagnosis
  • Rule Out
  • Prognosis
  • Formula
  • Treatment
  • Algorithm
  • Disease
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    Specialty
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    Chief Complaint
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    Organ System
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    Treatment of Malignant Pleural Mesothelioma(beta)

    Based on guidelines from the American Society of Clinical Oncology.

    Diagnosis

    Thoracentesis

    Strong recommendation
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    Intermediate quality evidence

    Thoracoscopic Biopsy

    Strong recommendation
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    High quality evidence

    Strong recommendation
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    High quality evidence

    Open Pleural Biopsy

    Moderate recommendation
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    Intermediate quality evidence

    Core Needle Biopsy

    Strong recommendation
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    Intermediate quality evidence

    Cytology

    Strong recommendation
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    Intermediate quality evidence

    Immunohistochemistry

    Strong recommendation
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    Intermediate quality evidence

    Pathological Subtypes

    Strong recommendation
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    High quality evidence

    Moderate recommendation
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    N/A

    Non-tissue-based Biomarkers Not Recommended

    Moderate recommendation
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    Intermediate quality evidence

    Tumor Genomic Sequencing Not Recommended

    Moderate recommendation
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    Intermediate quality evidence

    Staging

    CT

    Strong recommendation
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    Intermediate quality evidence

    FDG PET/CT

    Strong recommendation
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    Intermediate quality evidence

    Abdominal CT

    Strong recommendation
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    Intermediate quality evidence

    MRI

    Moderate recommendation
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    Intermediate quality evidence

    Mediastinoscopy and/or Endobronchial US

    Strong recommendation
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    Intermediate quality evidence

    Thoracoscopy

    Moderate recommendation
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    Intermediate quality evidence

    Laparoscopy

    Strong recommendation
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    Intermediate quality evidence

    Staging

    Strong recommendation
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    High quality evidence

    Tumor Measurement

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Tumor Response Classification

    Strong recommendation
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    Intermediate quality evidence

    Treatment

    Chemotherapy

    Strong recommendation
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    Intermediate quality evidence

    Moderate recommendation
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    N/A

    Moderate recommendation
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    Low quality evidence

    Strong recommendation
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    High quality evidence

    Moderate recommendation
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    High quality evidence

    Moderate recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Moderate recommendation
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    Low quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Moderate recommendation
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    Low quality evidence

    Moderate recommendation
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    Low quality evidence

    Moderate recommendation
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    Low quality evidence

    Strong recommendation
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    Low quality evidence

    Surgical Cytoreduction

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    High quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Moderate recommendation
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    Low quality evidence

    Moderate recommendation
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    Intermediate quality evidence

    Moderate recommendation
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    Intermediate quality evidence

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    Low quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Radiation Therapy

    Moderate recommendation
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    High quality evidence

    Moderate recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Moderate recommendation
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    N/A

    Strong recommendation
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    Intermediate quality evidence

    Moderate recommendation
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    Intermediate quality evidence

    Moderate recommendation
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    Intermediate quality evidence

    Strong recommendation
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    N/A

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    Strong recommendation
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    Intermediate quality evidence

    How strong is the ASCO's recommendation?

    Strong recommendation
    High confidence that recommendation reflects best practice, based on (1) strong evidence for true net effect (benefits > harms); (2) consistent results, with no or minor exceptions; (3) minor or no concerns about study quality; and/or (4) extent of panelists’ agreement.
    Moderate recommendation
    Moderate confidence that recommendation reflects best practice, based on (1) good evidence for true net effect (benefits > harms); (2) consistent results, with minor and/or few exceptions; (3) minor and/or few concerns about study quality; and/or (4) extent of panelists’ agreement.
    Some confidence that recommendation offers the best current guidance for practice, based on (1) limited evidence for true net effect (benefits > harms); (2) consistent results, but with important exceptions; (3) concerns about study quality; and/or (4) extent of panelists’ agreement.
    High quality evidence
    High confidence that available evidence reflects true magnitude and direction of net effect (i.e., balance of benefits vs harms) and that further research is very unlikely to change either magnitude or direction of this net effect.
    Intermediate quality evidence
    Moderate confidence that available evidence reflects true magnitude and direction of net effect. Further research is unlikely to alter the direction of the net effect; however, it might alter the magnitude of the net effect.
    Low quality evidence
    Low confidence that available evidence reflects true magnitude and direction of the net effect. Further research may change either the magnitude and/or direction of this net effect.
    Insufficient evidence
    Evidence is insufficient to discern true magnitude and direction of net effect. Further research may better inform the topic. The use of the consensus opinion of experts is reasonable to inform outcomes related to the topic.
    N/A
    No evidence was assigned.