Calc Function

  • Diagnosis
  • Rule Out
  • Prognosis
  • Formula
  • Treatment
  • Algorithm
  • Disease
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    Specialty
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    Chief Complaint
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    Organ System
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    Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes(beta)

    Official guideline of the American College of Gastroenterology.

    Lynch Syndrome (LS)

    Lynch Syndrome (LS)

    Strong recommendation
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    Conditional recommendation
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    Moderate quality evidence

    Conditional recommendation
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    Low quality evidence

    Conditional recommendation
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    Very low quality evidence

    Conditional recommendation
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    Very low quality evidence

    Conditional recommendation
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    Low quality evidence

    Conditional recommendation
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    Moderate quality evidence

    Adenomatous Polyposis Syndromes

    Familial Adenomatous Polyposis (FAP)/MUTYH-associated Polyposis (MAP)/Attenuated Polyposis

    Strong recommendation
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    Moderate quality evidence

    Strong recommendation
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    Low quality evidence

    Strong recommendation
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    Very low quality evidence

    Conditional recommendation
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    Low quality evidence

    Conditional recommendation
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    Very low quality evidence

    Strong recommendation
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    Low quality evidence

    Hamartomatous Polyposis Syndromes

    Peutz-Jeghers Syndrome (PJS)

    Conditional recommendation
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    Low quality evidence

    Juvenile Polyposis Syndrome (JPS)

    Conditional recommendation
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    Very low quality evidence

    Conditional recommendation
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    Low quality evidence

    Conditional recommendation
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    Very low quality evidence

    Cowden Syndrome (PTEN Hamartoma Tumor Syndrome)

    Conditional recommendation
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    Low quality evidence

    Serrated/Hyperplastic Polyposis Syndrome

    Conditional recommendation
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    Low quality evidence

    Conditional recommendation
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    Low quality evidence

    Conditional recommendation
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    Very low quality evidence

    Hereditary Pancreatic Cancer

    Hereditary Pancreatic Cancer

    Conditional recommendation
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    Very low quality evidence

    Conditional recommendation
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    Very low quality evidence

    Conditional recommendation
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    Low quality evidence

    Hereditary Gastric Cancer

    Hereditary Diffuse Gastric Cancer

    Conditional recommendation
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    Low quality evidence

    How strong is the ACG's recommendation?

    Strong recommendation
    Intervention's desirable effects clearly outweigh undesirable effects.
    Conditional recommendation
    Uncertainty in tradeoffs between desirable & undesirable effects of intervention.
    Moderate quality evidence
    Further research would be likely to have an impact on the confidence in the estimate of effect.
    Moderate for screening; very low for surveillance, initiation age
    Low quality evidence
    Further research would be expected to have an impact on the confidence in the estimate of effect.
    Very low quality evidence
    Any estimate of effect is very uncertain.