MDCalc

HERDOO2 Rule for Discontinuing Anticoagulation in Unprovoked VTE

Identifies low-risk women who can safely discontinue VTE treatment.

Use in women ≥18 years old with unprovoked VTE. Do not use in patients with any of the following at the time of VTE diagnosis: leg fracture, lower-extremity plaster cast, immobilization >3 days, general anesthesia <3 months before, or cancer diagnosis within 5 years.

Post-thrombotic signs
Hyperpigmentation, edema, or redness (either leg)
D-dimer level
BMI, kg/m²
Age, years

Result:

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Advice

The benefits and known risks of discontinuing anticoagulation in those deemed low-risk should be discussed with the patient.