MDCalc

HINTS for Stroke in Acute Vestibular Syndrome

Identifies potential stroke in patients with acute vestibular syndrome (AVS).

Proper administration of the test itself is critical to using this calculator. See a video from the authors here.

Horizontal head impulse test (h-HIT)
Observation of nystagmus
Test of skew

Result:

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Advice

  • A “benign” HINTS examination, in the absence of other neurological deficits, suggests a peripheral localization, and investigation and management can be directed at this possibility.

  • A “dangerous” HINTs examination strongly supports a central lesion, and appropriate workup is required.

  • An important exception is that acute ischemia of the anterior inferior cerebellar artery territory can produce a “benign” HINTS examination. This possibility should be considered in patients with vascular risk factors, sudden-onset symptoms, or concurrent ipsilateral hearing loss.

Management

  • Consider neurologist, neuro-ophthalmologist, or neuro-otologist consultation in the disposition of AVS patients, as even if the HINTS examination is “benign,” many peripheral lesions are amenable to time-sensitive therapy (eg. vestibular neuronitis).

  • Vestibular suppressants, such as prochlorperazine, can impede recovery and compensation of a peripheral vestibular lesion, and thus should be very rarely and sparingly used (if at all).

  • Patients with a “dangerous” HINTS examination are generally admitted for neuroimaging and appropriate directed therapies (e.g. stroke).

Critical Actions

HINTS does not replace a detailed history and general neurological examination, and care must be taken not to ignore other non-vestibular diagnoses (e.g. the vertiginous aura of superior temporal lobe seizures).