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    Infective Endocarditis (IE) Mortality Risk Score

    Predicts mortality at 6 months in patients with infective endocarditis.
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    When to Use
    Pearls/Pitfalls
    Why Use

    Patients with confirmed IE to estimate mortality.

    • Infective endocarditis (IE) has an overall 6-month mortality of approximately 25% in all-comers.
    • Older age and history of dialysis appear to be the highest risk patient factors; IE complications also suggest a high mortality as well.
    • Surgery is associated with a lower mortality rate but is infrequent in the high-risk cohort of patients.
    • Mortality ranges from 10% in the lowest risk quintile to 53% in the highest-risk quintile.

    Points to keep in mind:

    • Surgery in this study was associated with lower mortality, but the highest risk patients were less likely to receive surgery (probably because they were high-risk surgical patients as well).
    • This study was performed in referral centers (likely tertiary and quaternary academic centers) with experience with endocarditis and cardiac surgery.

    The IE Mortality Score provides an objective mortality estimate.

    Host Factors
    ≤45
    0
    46-60
    +2
    61-70
    +3
    >70
    +4
    No
    0
    Yes
    +3
    Infective Endocarditis (IE) Factors
    No
    0
    Yes
    +2
    No
    0
    Yes
    +1
    No
    0
    Yes
    -1
    No
    0
    Yes
    +1
    No
    0
    Yes
    -2
    No
    0
    Yes
    +1
    No
    0
    Yes
    +1
    Infective Endocarditis (IE) Complications
    No
    0
    Yes
    +3
    No
    0
    Yes
    +2
    No
    0
    Yes
    +2
    No
    0
    Yes
    +2
    No
    0
    Yes
    -2

    Result:

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    Next Steps
    Evidence
    Creator Insights

    Advice

    Patients with IE may benefit from consultation with cardiothoracic surgery and infectious disease services.

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    About the Creator
    Dr. Andrew Wang
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