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    Liver Decompensation Risk after Hepatectomy for Hepatocellular Carcinoma (HCC)

    Predicts risk of liver decompensation after hepatectomy for hepatocellular carcinoma (HCC).
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    Formula

    Liver decompensation risk algorithm

    Portal hypertension = at least F1 esophageal varices (i.e., small and straight) on endoscopy OR platelets <100,000/μL with splenomegaly (>12 cm diameter).

    Extension of hepatectomy: major resection = removal of ≥3 adjacent segments.

    Facts & Figures

    Interpretation:

    Risk Group

    Liver decompensation rate

    Median length of stay

    Risk of mortality due to liver failure

    Low

    4.9%

    7 days

    4.4%

    Intermediate

    28.6%

    8 days

    9.0%

    High

    60.0%

    11 days

    25.0%

    Dr. Vincenzo Mazzaferro

    About the Creator

    Vincenzo Mazzaferro, MD, is a professor of medicine and director of the Gastrointestinal and Hepato-Pancreatic Surgery and Liver Transplantation Unit at the Istituto Nazionale dei Tumori in Milan, Italy. He is an avid researcher of liver transplantation and studies treatment of metastatic cancers to the liver and novel treatments of tumors. Dr. Mazzaferro’s research group was responsible for the development of the Milan Criteria, which has been adopted as a transplant guideline in many countries.

    To view Dr. Vincenzo Mazzaferro's publications, visit PubMed

    About the Creator
    Dr. Vincenzo Mazzaferro