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    MDRD GFR Equation

    Estimates glomerular filtration rate based on creatinine and patient characteristics.
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    INSTRUCTIONS

    Only for chronic kidney disease (CKD), not accurate for acute renal failure. Also, note that a later study indicates the MDRD may underestimate the actual GFR in healthy patients by up to 29%.

    Pearls/Pitfalls
    The Modification of Diet in Renal Disease Study (MDRD) equation cannot be used for acute renal failure. It is only useful in estimating glomerular filtration rate (GFR) in stable chronic kidney disease.
    years
    mg/dL

    Result:

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    Advice

    Always consider and avoid nephrotoxic medications; patients with worsening GFR/CKD may require nephrology consultation.

    Formula

    GFR = 186 × Serum Cr-1.154 × age-0.203 × 1.212 (if patient is black) × 0.742 (if female)

    Use serum Cr in mg/dL for this formula.

    Dr. Andrew S. Levey

    About the Creator

    Andrew S. Levey, MD, is the chief of the nephrology division at Tufts Medical Center and the Dr. Gerald J. and Dorothy R. Friedman Professor at Tufts University School of Medicine. His clinical interests include chronic kidney disease (CKD), diabetic kidney disease, and systemic lupus erythematosus. Dr. Levey’s research focuses on laboratory measures to estimate kidney function, new therapies, and the development of clinical practice guidelines for CKD.

    To view Dr. Andrew S. Levey's publications, visit PubMed