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    MDRD GFR Equation

    Estimates glomerular filtration rate based on creatinine and patient characteristics.
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    INSTRUCTIONS

    Only for chronic kidney disease (CKD); not accurate for acute renal failure. Also, note that a later study indicates the MDRD may underestimate the actual GFR in healthy patients by up to 29%. This calculator uses the 4-variable equation from Levey 2006, as it has been recalibrated for differences in the lab testing of creatinine.

    Pearls/Pitfalls
    The Modification of Diet in Renal Disease Study (MDRD) equation cannot be used for acute renal failure. It is only useful in estimating glomerular filtration rate (GFR) in stable chronic kidney disease.
    Female
    Male
    No
    Yes
    years
    mg/dL

    Result:

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    Next Steps
    Evidence
    Creator Insights

    Advice

    Always consider and avoid nephrotoxic medications; patients with worsening GFR/CKD may require nephrology consultation.

    CKD Stage

    GFR, mL/min/1.73 m2

    I

    ≥90

    II

    60–89

    IIIa

    45–59

    IIIb

    30–44

    IV

    15–29

    V

    <15

    About the Creator
    Dr. Andrew S. Levey
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