MDCalc

Michigan Risk Score for PICC-Related Thrombosis

Predicts risk of DVT in patients with peripherally inserted central catheter (PICC).

Limited external validation performed; use with caution.

Another central venous catheter present
At the time of index PICC placement
WBC >12.0 × 10⁹/µL
At the time of index PICC placement
Number of PICC lumens
History of VTE
Active cancer
On chemotherapy or admitted for cancer-related reasons

Result:

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Advice
  • Risk of upper extremity DVT increases with Michigan Risk Score Class.
  • Compared with Class I:
    • Class II has a twofold higher risk of thrombosis.
    • Class III has a threefold higher risk.
    • Class IV has an eightfold higher risk.
  • A Class I score is not necessarily “safe” (incidence of DVT ~1%).
  • Carefully consider the risks and benefits of using a PICC, especially if the risk of thrombosis is high.
  • Strongest predictors for DVT risk were:
    • Triple-lumen PICCs.
    • PICCs placed in patients with a history of VTE in the past 30 days.
    • PICCs placed in the setting of active cancer.
  • Consider alternative devices (e.g. central venous catheters, ports, tunneled catheters) that can be placed in larger veins, if appropriate.
Critical Actions
  • This tool is meant to risk stratify patients who have a potential risk for PICC-related upper extremity DVT, not to diagnose DVT.
  • If deemed appropriate, anticoagulation should not be withheld from patients who require it as part of the treatment for their diagnosis.
  • Prior to initiating any anticoagulant therapy, a patient’s bleeding risk should be evaluated.