MDCalc

Milan Criteria for Liver Transplantation

Assess suitability of patients for liver transplant with cirrhosis and hepatocellular carcinoma, recommended by AASLD guidelines.

Single tumor with diameter ≤5 cm
Up to 3 tumors each with diameter ≤3 cm
Extra-hepatic involvement
Major vessel involvement

Result:

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Advice
  • In addition to standard workup for HCC, patients who fulfill the Milan Criteria should undergo full evaluation for OLT, including but not limited to assessment for comorbid conditions, appropriate laboratory studies, calculation of MELD, hepatology consultation, surgical evaluation, and referral to transplant center (Martin 2014).
  • Monitor for potentially treatable hepatic decompensation (ascites, encephalopathy, variceal bleeding).