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Modified Response Evaluation Criteria in Solid Tumors (mRECIST)

Measures treatment response, specifically to cytotoxic drugs, based on tumor shrinkage.

Use in liver lesions meeting the following criteria:

  • Can be accurately measured in at least one dimension as 10 mm or more (measure longest diameter).
  • Suitable for repeat measurement.
  • Intratumoral arterial enhancement on contrast-enhanced CT or MRI.
mm
mm

Advice

  • Contrast-enhanced CT or MRI is the imaging modality of choice for evaluating lesions.
  • European Association for the Study of the Liver (EASL) guidelines recommend evaluating for mRECIST criteria 1 month after undergoing treatment (surgery, locoregional therapy or initiation of systemic chemotherapy).

Management

recist treatment hcc
 
CR, complete response. PR, partial response. SD, stable disease. PD, progressive disease. IR, incomplete response.