PECARN Rule for Low Risk Febrile Infants 29-60 Days Old
This calculator is not yet externally validated. While derived in infants aged 0-60 days, the creators recommend using this calculator only in infants aged 29-60 days (i.e., do not use in infants 28 days or younger), due to elevated herpes meningoencephalitis risk and and limited numbers of episodes of bacterial meningitis in that age group (see Pearls/Pitfalls and Creator Insights for details).
Does not apply to ill-appearing infants. The rule is intended to be one-directional: it may help rule out serious bacterial infection (SBI) in patients who are “low risk”, but the converse is not true (i.e., patients who are “not low risk” by the rule do not necessarily have SBI).
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