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    Patent Pending

    Pittsburgh Response to Endovascular therapy (PRE) Score

    Identifies patients with anterior circulation large vessel occlusion (LVO) strokes likely to benefit from endovascular therapy.
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    BEFORE USE

    Use in patients ≥18 years old, presenting within 8 hours of symptom onset, with anterior circulation (i.e., internal carotid, M1, or M2) LVO stroke. Measure ASPECTS using most recent CT imaging data. Apply with caution to patients with baseline morbidities.

    When to Use
    Pearls/Pitfalls
    Why Use
    years
    points
    points
    About the Creator
    Dr. Srikant Rangaraju
    Content Contributors
    • Syed Ali Raza, MD

    Result:

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    Next Steps
    Evidence
    Creator Insights

    Management

    • Patients with PRE Score -24 to +49 are likely to derive the maximum benefit from endovascular reperfusion therapy if successful revascularization, i.e. TICI (Thrombolysis In Cerebral Infarction) grade 2b/3, is achieved.
    • Patients with PRE Score ≥50 are least likely to benefit from endovascular therapy. Rate of good outcome (mRS 0-2) or final infarct size was not affected by TICI grade 2b/3 reperfusion in the PRE Score ≥50 group.

    Critical Actions

    Use the PRE Score as an adjunct to clinical judgment, not a replacement.

    Content Contributors
    • Syed Ali Raza, MD