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    Patent Pending

    POMPE-C Tool for Pulmonary Embolism Mortality

    Predicts mortality for cancer patients with PE.
    When to Use
    Pearls/Pitfalls
    Why Use

    In the setting of a patient with known cancer who has been diagnosed with a pulmonary embolism, the POMPE-C can be used to estimate their mortality.

    The POMPE-C Prediction Tool was risk stratifies patients diagnosed with pulmonary embolism and have active cancer.

    • The POMPE-C prediction tool predicts mortality directly (at 30 days), not a risk category of mortality.
    • Active cancer has been shown to be a risk factor for PE, but less so for cancer in remission.
    • The POMPE-C has not been validated for incidental PE (PE found on imaging but without symptoms), though a small sample was identified and found to be low-risk overall.
    • The POMPE-C may be more accurate in predicting outcome than the PESI Score in the setting of patients with active cancer.
    • The POMPE-C has not yet been validated for selecting patients for outpatient management (though there is potential for future research).
    • Risk stratification is a vital part of the evaluation of a patient diagnosed with PE.
    • Most risk-stratification tools use cancer as a prognostic indicator, but no risk stratification tool exists for those patients with known cancer.
    • Those patients that are determined to be low risk (score ≤5%) may warrant outpatient management (though this has not been validated).
    No
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    breaths/min
    lbs
    %

    Result:

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    Next Steps
    Evidence
    Creator Insights
    Dr. Jeffrey Kline

    About the Creator

    Jeffrey Kline, MD, is a professor of emergency medicine and physiology and the vice chair of research at Indiana University. Among other research, he has conducted clinical studies using breath-based methods to diagnose and assess the severity of PE. He co-founded BreathQuant Medical Systems Inc to advance practical applications of 16 patents for medical devices. Dr. Kline has published over 50 manuscripts in the area of PE.

    To view Dr. Jeffrey Kline's publications, visit PubMed

    Are you Dr. Jeffrey Kline? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.
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