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      Calc Function

    • Calcs that help predict probability of a diseaseDiagnosis
    • Subcategory of 'Diagnosis' designed to be very sensitiveRule Out
    • Disease is diagnosed: prognosticate to guide treatmentPrognosis
    • Numerical inputs and outputsFormula
    • Med treatment and moreTreatment
    • Suggested protocolsAlgorithm

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    Patent Pending

    PROMISE Score for Malignant Pleural Effusion

    Predicts 3-month mortality in patients with malignant pleural effusion.
    Favorite
    When to Use
    Pearls/Pitfalls

    Use in patients with late-stage cancer and malignant pleural effusion, either from primary lung cancer or metastasis to lung.

    TIMP1 is not available at all institutions, but if available, can add to the prognostic power of the score.

    No
    Yes
    No
    Yes
    ≥16
    14 to <16
    12 to <14
    10 to <12
    <10
    <4
    4 to <6.3
    6.3 to <10
    10 to <15.8
    ≥15.8
    <3
    3 to <10
    10 to <32
    32 to <100
    ≥100
    0-1
    2-4
    Mesothelioma
    All other types of cancer
    Lung
    Unknown
    <40
    40 to <160
    ≥160

    Result:

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    Next Steps
    Evidence
    Creator Insights

    Advice

    • Consider optimizing supportive care and avoiding invasive interventions in patients with higher mortality to improve quality of life.
    • Elevated CRP is nonspecific. Use clinical judgment and ensure that pleural fluid is carefully evaluated for potential coexisting infectious/inflammatory etiologies.
    Reviewed By
    • Sachin Patel, MD
    About the Creator
    Dr. Ioannis Psallidas
    Are you Dr. Ioannis Psallidas?
    Reviewed By
    • Sachin Patel, MD